2025.4.〜2026.3.

学術論文(Journal articles)

  1. Construction of high protein-producing mutant yeast strains via point and structural mutageneses and their use for carotenoid production. R. Yamada*, Y. Inoue, Y. Karitani, R. Sakaguchi, T. Matsumoto, H. Ogino, Journal of Biotechnology, 409, 77–84 (2025)
  2. Construction of yeast with extremely high 2,3-butanediol tolerance by introducing point and structural mutations and partial elucidation of the mechanism of 2,3-butanediol tolerance. K. Nakamura, R. Yamada*, T. Matsumoto, H. Ogino, Applied Microbiology and Biotechnology, 109, 227 (2025)
  3. Improvement of D-lactic acid production from methanol by metabolically engineered Komagataella phaffii via ultra-violet mutagenesis. Y. Inoue, K. Nakamura, R. Yamada*, T. Matsumoto, H. Ogino, Metabolic engineering communications, 20, e00262 (2025)
  4. Sortase A-mediated ligation facilitates metabolic channeling in Saccharomyces cerevisiae. A. Saito, H. Taniguchi, T. Matsumoto*, R. Yamada, H. Ogino, ACS Synthetic Biology, 14, 1567 (2025)

学術講演発表(Conference presentations)

  1. 2025年度カロテノイド若手の会(2025年11月,名古屋)井上義文,山田亮祐,松本拓也,荻野博康,「メタノール資化性酵母のrDNA遺伝子座への複数遺伝子組込みによる β-カロテン生産」
  2. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) M. Takahashi, R. Yamada, T. Matsumoto, H. Ogino,「Enhanced wastewater treatment by co-immobilizing microalgae and yeast in beads」
  3. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) T. Matsumoto, M. Hashimoto, K. Yoshino, R. Yamada, H. Ogino,「Construction of an extracellular electron transfer system on liposomes as novel carrier for chemical reaction」
  4. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) M. Hashimoto, T. Matsumoto, R. Yamada, H. Ogino,「Sortase A-mediated enzyme assembly on multimeric protein for improving mevalonate production」
  5. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) Y. Kurauchi, T. Matsumoto, R. Yamada, H. Ogino,「Engineering Escherichia coli for PET degradation using surface-displayed enzyme systems」
  6. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) Y. Inoue, R. Yamada, T. Matsumoto, H. Ogino,「Production of β-carotene from methanol by multi-gene integration into the rDNA locus of Komagataella phaffi」
  7. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) A. Nakamura, T. Matsumoto, R. Yamada, H. Ogino,「Enhanced 3-hydroxypropionic acid production through metabolic engineering of yeast mitochondria and peroxisomes」
  8. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) S. Uemura, R. Yamada, T. Matsumoto, H. Ogino,「Construction of lactic acid-tolerant yeast by simultaneous point and structural mutagenesis」
  9. International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025 (2025.11. Okinawa) R. Yamada,「Optimizing gene expression for bio-based chemical production in yeast via machine learning approaches」
  10. 化学工学会第56回秋季大会(2025年9月,東京)永谷拓士,水野ひなた,松本拓也,山田亮祐,冨田健一,荻野博康,「有機溶媒耐性プロテアーゼのアラニルアラニン合成活性の向上」
  11. 第77回日本生物工学会大会(2025年9月,広島)井上義文,山田亮祐,松本拓也,荻野博康「Komagataella phaffiiのrDNA遺伝子座への複数遺伝子導入によるメタノールからの β-カロテン生産」
  12. 第77回日本生物工学会大会(2025年9月,広島)上村颯希,山田亮祐,松本拓也,荻野博康「点変異と構造変異の導入による酵母の乳酸耐性向上」
  13. 生物工学若手研究者の集い夏のセミナー(2025年7月,福岡)井上義文,山田亮祐,松本拓也,荻野博康,「Komagataella phaffiiのrDNA遺伝子座への遺伝子導入によるメタノールからのD-乳酸生産高生産株の構築」
  14. 生物工学若手研究者の集い夏のセミナー(2025年7月,福岡)高橋美郁,山田亮祐,松本拓也,荻野博康,「微細藻類と酵母の共固定化ビーズによる排水処理」
  15. 学術変革領域研究(A)「生物を凌駕する無細胞分子システムのボトムアップ構築学」第5回領域会議(2025年4月,東京)松本拓也,「細胞外電子伝達タンパク質を提示したリポソームキャリアーの構築」

受賞(Awards)

  1. 井上義文,優秀発表賞(2025年11月),2025年度カロテノイド若手の会