業績

業 績

    • *Setogawa S, Okauchi T, Hu D, Wada Y, Hikishima K, Onoe H, Nishizawa K, Sakayori N, Miyawaki H, Kitanishi T, Mizuseki K, Cui YL, *Kobayashi K (2025)
      Acquisition of auditory discrimination mediated by different processes through two distinct circuits linked to the lateral striatum.
      eLife 13, RP97326. [PubMed] [DOI]

    • Kajiya R, *Miyawaki H, Nakahara H, *Mizuseki K (2025)
      Firing Activities of REM- and NREM-Preferring Neurons Are Differently Modulated by Fast Network Oscillations and Behavior in the Hippocampus, Prelimbic Cortex, and Amygdala.
      eNeuro 12 (5) ENEURO.0575-24.2025. [PubMed] [DOI]

    • *Kuroki S, Mizuseki K (2025)
      Excitation–Inhibition Balance Controls Synchronization in a Simple Model of Coupled Phase Oscillators.
      Neural Computation 37(7):1353-1372. [PubMed] [DOI]

    • Iwase M, Diba K, Pastalkova E, *Mizuseki K (2024)
      Dynamics of spike transmission and suppression between principal cells and interneurons in the hippocampus and entorhinal cortex.
      Hippocampus 34:393-421. [PubMed] [DOI]

    • *Kuroki S, Mizuseki K (2024)
      CA3 circuit model compressing sequential information in theta oscillation and replay.
      Neural Comput 36(4):501-548. [PubMed] [DOI]

    • Nakai S, *Kitanishi T, *Mizuseki K (2024)
      Distinct manifold encoding of navigational information in the subiculum and hippocampus.
      Sci Adv 10: eadi4471. [PubMed] [DOI]

    • Maboudi K, Giri B, Miyawaki H, Kemere C, *Diba K(2024)
      Retuning of hippocampal representations during sleep.
      Nature 629 (8012), 630-638. [PubMed] [DOI]

    • Setogawa S, Kanda R, Tada S, Hikima T, Saitoh Y, Ishikawa M, Nakada S, Seki F, Hikishima K, Matsumoto H, Mizuseki K, Fukayama O, Osanai M, Sekiguchi H, *Ohkawa N (2023)
      A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortices in mice.
      Mol Brain 16:38. [PubMed] [DOI]

    • †*Mizuseki K, †Miyawaki H (2023)
      Fast network oscillations during non-REM sleep support memory consolidation.
      Neurosci Res 189: 3-12. [PubMed] [DOI]

    • †Li Q, †Takeuchi T, Wang J, Gellért L, Barcsai L, Pedraza LK, Nagy AJ, Kozák G, Nakai S, Kato S, Kobayashi K, Ohsawa M, Horváth G, Kékesi G, Lőrincz ML, Devinsky O, Buzsáki G, *Berényi A (2023)
      Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents.
      Neuron 111 (13), 2065-2075. e5. [PubMed] [DOI]

    • Yoshida R, Takamori M, Matsumoto H, Miura K (2023)
      Tropical Support Vector Machines: Evaluations and Extension to Function Spaces.
      Neural Networks 157:77–89. [PubMed] [DOI]

    • Takahashi M, Sukowati EW, Nomura S, Kato A, Mizuseki K, Watanabe Y, *Mukai H (2022)
      Impact of tumoral structure and bacterial species on growth and biodistribution of live bacterial therapeutics in xenografted tumours.
      J Drug Target 31(2):194-205. [PubMed] [DOI]

    • *Mizuseki K, *Kitanishi T (2022)
      Oscillation-coordinated, noise-resistant information distribution via the subiculum.
      Curr Opin Neurobiol 75:102556. [PubMed] [DOI]

    • *Miyawaki H, *Mizuseki K (2022)
      De novo inter-regional coactivations of preconfigured local ensembles support memory.
      Nat Commun 13:1272. [PubMed] [DOI]

    • *Kitanishi T, Tashiro M, Kitanishi N, *Mizuseki K (2022)
      Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions.
      Commun Biol 5:149. [PubMed] [DOI]

    • Sakayori N, Katakura M, Setogawa, S, Sugita M, *Kobayashi K (2022)
      Characterization of the fatty acid profile in the ventral midbrain of mice exposed to dietary imbalance between omega-6 and omega-3 fatty acids during specific life stages.
      BMC Research Notes 15(1), 285. [PubMed] [DOI]

    • Vöröslakos M, Miyawaki H, Royer S, Diba K, Yoon E, Petersen PC, *Buzsáki G (2021)
      3D-printed Recoverable Microdrive and Base Plate System for Rodent Electrophysiology.
      Bio Protoc 11(16):e4137.. [PubMed] [DOI]

    • *Takeuchi Y, Nagy AJ, Barcsai L, Li Q, Ohsawa M, Mizuseki K, *Berenyi A (2021)
      The medial septum as a potential target for treating brain disorders associated with oscillopathies.
      Front Neural Circuits 15:701080. [PubMed] [DOI]

    • *Kitanishi T, Umaba R, *Mizuseki K (2021)
      Robust information routing by dorsal subiculum neurons.
      Sci Adv 7(11):eabf1913. [PubMed] [DOI]

    • Umaba R, *Kitanishi T, *Mizuseki K (2021)
      Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.
      Neurosci Res 171, 1-8. [PubMed] [DOI]

    • *Kurikawa T, Mizuseki K, Fukai T (2021)
      Oscillation-Driven Memory Encoding, Maintenance, and Recall in an Entorhinal-Hippocampal Circuit Model.
      Cereb Cortex 31(4), 2038-2057. [PubMed] [DOI]

    • Robinson KC, Kemény LV, Fell GL, Hermann AL, Allouche J, Ding W, Yekkirala A, Hsiao JJ, Su MY, Theodosakis N, Kozak G, Takeuchi Y, Shen S, Berenyi A, Mao J, Woolf CJ, *Fisher DE(2021)
      Reduced MC4R signaling alters nociceptive thresholds associated with red hair.
      Science Advances 7 (14), eabd1310. [PubMed] [DOI]

    • Iwase M, Kitanishi T, *Mizuseki K (2020)
      Cell type, sub-region, and layer-specific speed representation in the hippocampal–entorhinal circuit.
      Sci Rep 10:1407. [PubMed] [DOI]

    • Tsutsui-Kimura I, Matsumoto H, Akiti K, Yamada M, Uchida N, *Watabe-Uchida M (2020)
      Distinct temporal difference error signals in dopamine axons in three regions of the striatum in a decision-making task.
      Neural Networks 157:77–89. [PubMed] [DOI]

    • Yamazaki SJ, Ohara K, Ito K, Kokubun N, Kitanishi T, Takaichi D, Yamada Y, Ikejiri Y, Hiramatsu F, Fujita K, Tanimoto Y, Yamazoe-Umemoto A, Hashimoto K, Sato K, Yoda K, Takahashi A, Ishikawa Y, Kamikouchi A, Hiryu S, Maekawa T, *Kimura KD (2019)
      STEFTR: A Hybrid Versatile Method for State Estimation and Feature Extraction From the Trajectory of Animal Behavior.
      Front Neurosci 13:626. [PubMed] [DOI]

    • Giri B, Miyawaki H, Mizuseki K, Cheng S, *Diba K (2019)
      Hippocampal Reactivation Extends for Several Hours Following Novel Experience.
      J Neurosci 39, 866-875. [PubMed] [PDF]

    • Kobayashi R, Kurita S, Kurth A, Kitano K, Mizuseki K, Diesmann M, Richmond BJ, *Shinomoto S (2019)
      Reconstructing neuronal circuitry from parallel spike trains.
      Nat Commun 10:4468. [PubMed]

    • Matsumoto N, *Kitanishi T, Mizuseki K (2019)
      The subiculum: Unique hippocampal hub and more.
      Neurosci Res 143, 1-12. [PubMed]

    • *Mizuseki K, Miyawaki H (2019)
      Hippocampal information processing and homeostatic regulation during REM and non-REM sleep.
      In: Handbook of Behavioral Neuroscience 30, 49-62: Elsevier. [PubMed]

    • Ohara S, Gianatti M, Itou K, Berndtsson CH, Doan TP, Kitanishi T, Mizuseki K, Iijima T, Tsutsui KI, *Witter MP (2019)
      Entorhinal Layer II Calbindin-Expressing Neurons Originate Widespread Telencephalic and Intrinsic Projections.
      Front Syst Neurosci 13:54. [PubMed]

    • Watanabe K, Sasaki AT, Tajima K, Mizuseki K, Mizuno K, *Watanabe Y (2019)
      Mental fatigue is linked with attentional bias for sad stimuli.
      Scientific reports 9:8797. [PubMed]

    • Watanabe K, Nozaki S, Goto M, Kaneko KI, Hayashinaka E, Irie S, Nishiyama A, Kasai K, Fujii K, Wada Y, Mizuno K, Mizuseki K, Doi H, *Watanabe Y (2019)
      PET imaging of (11)C-labeled coenzyme Q10: Comparison of biodistribution between [(11)C]ubiquinol-10 and [(11)C]ubiquinone-10.
      Biochemical and biophysical research communications 512, 611-615. [PubMed]

    • Miyawaki H, Watson BO, *Diba K (2019)
      Neuronal firing rates diverge during REM and homogenize during non-REM.
      Scientific Reports 9 (1):689. [PubMed] [DOI]

    • *Mizuseki K, Miyawaki H (2017)
      Hippocampal information processing across sleep/wake cycles.
      Neurosci Res 118, 30-47. [PubMed]

    • Kitanishi T, Ito HT, Hayashi Y, Shinohara Y, *Mizuseki K, *Hikida T (2017)
      Network mechanisms of hippocampal laterality, place coding, and goal-directed navigation.
      J. Physiol. Sci. 67, 247-258. [PubMed]

    • Durand S, Iyer R, Mizuseki K, de VS, Mihalas S, *Reid RC (2016)
      A Comparison of Visual Response Properties in the Lateral Geniculate Nucleus and Primary Visual Cortex of Awake and Anesthetized Mice.
      J. Neurosci. 36, 12144-12156. [PubMed] [PDF]

    • *Diba K, Amarasingham A, Mizuseki K, Buzsáki G (2014)
      Millisecond timescale synchrony among hippocampal neurons.
      J. Neurosci. 34, 14984-14994. [PubMed] [PDF]

    • Schomburg EW, Fernández-Ruiz A, Mizuseki K, Berényi A, Anastassiou CA, Koch C, *Buzsáki G (2014)
      Theta phase segregation of input-specific gamma patterns in entorhinal-hippocampal networks.
      Neuron 84, 470-485. [PubMed]

    • *Mizuseki K, Diba K, Pastalkova E, Teeters J, Sirota A, *Buzsáki G (2014)
      Neurosharing: Large-scale data sets (spike, LFP) recorded from the hippocampal-entorhinal system in behaving rats.
      F1000 Research. 3:98. [PubMed]

    • Agarwal G, Stevenson IH, Berenyi A, Mizuseki K, *Buzsaki G, *Sommer FT (2014)
      Spatially distributed local fields in the hippocampus encode rat position.
      Science 344, 626-630. [PubMed]

    • *Buzsaki G, Mizuseki K (2014)
      The log-dynamic brain: how skewed distributions affect network operations.
      Nat. Rev. Neurosci. 15, 264-278. [PubMed]

    • Sullivan D, Mizuseki K, Sorgi A, *Buzsaki G (2014)
      Comparison of sleep spindles and theta oscillations in the hippocampus.
      J. Neurosci. 34, 662-674. [PubMed] [PDF]

    • Mizuseki K, *Buzsaki G (2014)
      Theta oscillations decrease spike synchrony in the hippocampus and entorhinal cortex.
      Philos. Trans. R. Soc. Lond B Biol. Sci. 369, 20120530. [PubMed]

    • *Mizuseki K, *Buzsaki G (2013)
      Preconfigured, skewed distribution of firing rates in the hippocampus and entorhinal cortex.
      Cell Rep. 4, 1010-1021. [PubMed]

    • *Taxidis J, Mizuseki K, Mason R, Owen MR (2013)
      Influence of slow oscillation on hippocampal activity and ripples through cortico-hippocampal synaptic interactions, analyzed by a cortical-CA3-CA1 network model.
      Front Comput. Neurosci. 7, 3. [PubMed]

    • *Stevenson IH, London BM, Oby ER, Sachs NA, Reimer J, Englitz B, David SV, Shamma SA, Blanche TJ, Mizuseki K, Zandvakili A, Hatsopoulos NG, Miller LE, Kording KP (2012)
      Functional connectivity and tuning curves in populations of simultaneously recorded neurons.
      PLoS. Comput. Biol. 8, e1002775. [PubMed]

    • Grosmark AD, Mizuseki K, Pastalkova E, Diba K, *Buzsaki G (2012)
      REM sleep reorganizes hippocampal excitability.
      Neuron 75, 1001-1007. [PubMed]

    • Vandecasteele M, MS, Royer S, Belluscio M, Berenyi A, Diba K, Fujisawa S, Grosmark A, Mao D, Mizuseki K, Patel J, Stark E, Sullivan D, Watson B, *Buzsaki G (2012)
      Large-scale recording of neurons by movable silicon probes in behaving rodents.
      J. Vis. Exp. e3568. [PubMed]

    • Mizuseki K, Royer S, Diba K, *Buzsaki G (2012)
      Activity dynamics and behavioral correlates of CA3 and CA1 hippocampal pyramidal neurons.
      Hippocampus 22, 1659-1680. [PubMed]

    • Belluscio M, Mizuseki K, Schmidt R, Kempter R, *Buzsaki G (2012)
      Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus.
      J. Neurosci. 32, 423-435. [PubMed] [PDF]

    • Mizuseki K, Diba K, Pastalkova E, *Buzsaki G (2011)
      Hippocampal CA1 pyramidal cells form functionally distinct sublayers.
      Nat. Neurosci. 14, 1174-1181. [PubMed]

    • Sullivan D, Csicsvari J, Mizuseki K, Montgomery S, Diba K, *Buzsaki G (2011)
      Relationships between hippocampal sharp waves, ripples, and fast gamma oscillation: influence of dentate and entorhinal cortical activity.
      J. Neurosci. 31, 8605-8616. [PubMed] [PDF]

    • Geisler C, Diba K, Pastalkova E, Mizuseki K, Royer S, *Buzsaki G (2010)
      Temporal delays among place cells determine the frequency of population theta oscillations in the hippocampus.
      Proc. Natl. Acad. Sci. U. S. A. 107, 7957-7962. [PubMed]

    • Mizuseki K, Sirota A, Pastalkova E, *Buzsaki G (2009)
      Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop.
      Neuron 64, 267-280. [PubMed]

    • *Itskov V, Pastalkova E, Mizuseki K, Buzsaki G, Harris KD (2008)
      Theta-mediated dynamics of spatial information in hippocampus.
      J. Neurosci. 28, 5959-5964. [PubMed] [PDF]

    • Isomura Y, Sirota A, Ozen S, Montgomery S, Mizuseki K, Henze DA, *Buzsaki G (2006)
      Integration and segregation of activity in entorhinal-hippocampal subregions by neocortical slow oscillations.
      Neuron 52, 871-882. [PubMed]

    • Yamazoe H, Kobori M, Murakami Y, Yano K, Satoh M, Mizuseki K, Sasai Y, *Iwata H (2006)
      One-step induction of neurons from mouse embryonic stem cells in serum-free media containing vitamin B12 and heparin.
      Cell Transplant. 15, 135-145. [PubMed]

    • Ikeda H, Osakada F, Watanabe K, Mizuseki K, Haraguchi T, Miyoshi H, Kamiya D, Honda Y, Sasai N, Yoshimura N, Takahashi M, *Sasai Y (2005)
      Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells.
      Proc. Natl. Acad. Sci. U. S. A 102, 11331-11336. [PubMed]

    • Yamazoe H, Murakami Y, Mizuseki K, Sasai Y, *Iwata H (2005)
      Collection of neural inducing factors from PA6 cells using heparin solution and their immobilization on plastic culture dishes for the induction of neurons from embryonic stem cells.
      Biomaterials 26, 5746-5754. [PubMed]

    • Watanabe K, Kamiya D, Nishiyama A, Katayama T, Nozaki S, Kawasaki H, Watanabe Y, Mizuseki K, *Sasai Y (2005)
      Directed differentiation of telencephalic precursors from embryonic stem cells.
      Nat. Neurosci. 8, 288-296. [PubMed]

    • Irioka T, Watanabe K, Mizusawa H, Mizuseki K, *Sasai Y (2005)
      Distinct effects of caudalizing factors on regional specification of embryonic stem cell-derived neural precursors.
      Brain Res. Dev. Brain Res. 154, 63-70. [PubMed]

    • Mizuseki K, Sakamoto T, Watanabe K, Muguruma K, Ikeya M, Nishiyama A, Arakawa A, Suemori H, Nakatsuji N, Kawasaki H, Murakami F, *Sasai Y (2003)
      Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells.
      Proc. Natl. Acad. Sci. U. S. A 100, 5828-5833. [PubMed]

    • Kawasaki H, Suemori H, Mizuseki K, Watanabe K, Urano F, Ichinose H, Haruta M, Takahashi M, Yoshikawa K, Nishikawa S, Nakatsuji N, *Sasai Y (2002)
      Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity.
      Proc. Natl. Acad. Sci. U. S. A 99, 1580-1585. [PubMed]

    • Kawasaki H, Mizuseki K, *Sasai Y (2002)
      Selective neural induction from ES cells by stromal cell-derived inducing activity and its potential therapeutic application in Parkinson’s disease.
      Methods Mol. Biol. 185, 217-227. [PubMed]

    • Sasai N, Mizuseki K, *Sasai Y (2001)
      Requirement of FoxD3-class signaling for neural crest determination in Xenopus.
      Development 128, 2525-2536. [PubMed]

    • Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S, Nishikawa SI, *Sasai Y (2000)
      Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.
      Neuron 28, 31-40. [PubMed]

    • †Matsui M, †Mizuseki K, Nakatani J, Nakanishi S, *Sasai Y (2000)
      Xenopus kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline.
      Proc. Natl. Acad. Sci. U. S. A 97, 5291-5296. [PubMed]

    • Nakatani J, Mizuseki K, Tsuda H, Nakanishi S, *Sasai Y (2000)
      Xenopus Xenf: an early endodermal nuclear factor that is regulated in a pathway distinct from Sox17 and Mix-related gene pathways.
      Mech. Dev. 91, 81-89. [PubMed]

    • Kishi M, Mizuseki K, Sasai N, Yamazaki H, Shiota K, Nakanishi S, *Sasai Y (2000)
      Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm.
      Development 127, 791-800. [PubMed]

    • Mizuseki K, †Kishi M, Shiota K, Nakanishi S, *Sasai Y (1998)
      SoxD: an essential mediator of induction of anterior neural tissues in Xenopus embryos.
      Neuron 21, 77-85. [PubMed]

  • Mizuseki K, Kishi M, Matsui M, Nakanishi S, *Sasai Y (1998)
    Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction.
    Development 125, 579-587. [PubMed]
equal contribution
* corresponding author
Name in bold Lab member