発表論文

研究業績（2008年以降）

【原著論文】

  1. Shineha R., Takeda K.F., Yamaguchi Y. & Koizumi N. (2024) A comparative analysis of attitudes towards genome-edited food among Japanese public and scientific community. PLoS ONE, 19, e0300107
  2. Yamamoto R., Higuchi S., Iwata, Y., Takeda, S., Koizumi, N. & Mishiba K-I. (2024) High β-carotene accumulation in transgenic eggplant fruits grown under artificial light. Plant Biotechnology, 41, 77-81
  3. Takeda, K.F., Yazawa, A., Yamaguchi, Y., Koizumi, N., & Shineha, R. (2023) Comparison of public attitudes toward five alternative proteins in Japan. Food Quality and Preference, 105, 104787
  4. Sho Takeda, Taisuke Togawa, Kei-ichiro Mishiba, Katsuyuki T Yamato, Yuji Iwata, Nozomu Koizumi (2022) IRE1-mediated cytoplasmic splicing and regulated IRE1-dependent decay of mRNA in the liverwort Marchantia polymorpha. Plant Biotechnol 39: 303–310 [PubMed]
  5. Rikako Hirata, Tomoya Makabe, Kei-ichiro Mishiba, Nozomu Koizumi, Samir M. Hamdan, Yuji Iwata (2022) Unpaired nucleotides on the stem of microRNA precursor are important for precise cleavage by Dicer-Like1 in Arabidopsis. Genes Cells 27: 280-292 [PubMed]
  6. Masato Nakamura, Mamoru Nozaki, Yuji Iwata, Nozomu Koizumi, Yasushi, Sato (2022) THESEUS1 is involved in tunicamycin-induced root growth inhibition, ectopic lignin deposition, and cell wall damageinduced unfolded protein response. Plant Biotechnol 39: 129-138 [J-STAGE]
  7. Misa Matsuda, Yuji Iwata, Nozomu Koizumi, Kei-ichiro Mishiba (2020) Zeocin-induced DNA double-strand breaks affect endoreduplication and cell size in radish cotyledon epidermis. Cytologia 85(3):245-249
  8. Kei-ichiro Mishiba, Kae Nishida, Naoto Inoue, Tomoya Fujiwara, Shunji Teranishi, Yuji Iwata, Satomi Takeda, Nozomu Koizumi (2020) Genetic engineering of eggplant accumulating β-carotene in fruit. Plant Cell Rep 39:1029-1039
  9. Kei-ichiro Mishiba, Yuji Iwata, Tomofumi Mochizuki, Atsushi Matsumura, Nanami Nishioka, Rikako Hirata, Nozomu Koizumi (2019) Unfolded protein-independent IRE1 activation contributes to multifaceted developmental processes in Arabidopsis. Life Sci Alliance2:e201900459
  10. Rikako Hirata, Kei-ichiro Mishiba, Nozomu Koizumi, Yuji Iwata (2019) Deficiency in the double-stranded RNA binding protein HYPONASTIC LEAVES1 increases sensitivity to the endoplasmic reticulum stress inducer tunicamycin in Arabidopsis. BMC Res Notes 12:580 [Open Access]
  11. Ayumi Hirohata, Izumi Sato, Kimihiko Kaino, Yuji Iwata, Nozomu Koizumi, Kei-ichiro Mishiba (2019) CRISPR/Cas9-mediated homologous recombination in tobacco. Plant Cell Rep 38:463-473
  12. Yuji Iwata, Tsukasa Iida, Toshihiro Matsunami, Yu Yamada, Kei-ichiro Mishiba, Takumi Ogawa, Tetsuya Kurata, Nozomu Koizumi (2018) Constitutive BiP protein accumulation in Arabidopsis mutants defective in a gene encoding chloroplastt-resident stearoyl-acyl carrier protein desaturase. Genes Cells 23:456-465 [PubMed]
  13. Misa Matsuda, Yuji Iwata, Nozomu Koizumi, Kei-ichiro Mishiba (2018) DNA double-strand breaks promote endoreduplication in radish cotyledon. Plant Cell Rep 37:913-921 [PubMed]
  14. Yuji Iwata, Tsuneyo Nishino, Nozomu Koizumi (2017) Overexpression of the endoplasmic reticulum stress-inducible gene TIN1 causes abnormal pollen surface morphology in Arabidopsis. Plant Biotechnol, 34, 173-176.
  15. Yuji Iwata, Fumika Yagi, Sae Saito, Kei-ichiro Mishiba, Nozomu Koizumi (2017) Inositol-requiring enzyme 1 affects meristematic division in roots under moderate salt stress in Arabidopsis. Plant Biotechnol, 34, 159-163.
  16. Yuji Iwata, Makoto Ashida, Chisa Hasegawa, Kazuki Tabara, Kei-ichiro Mishiba, Nozomu Koizumi (2017) Activation of the Arabidopsis membrane-bound transcription factor bZIP28 is mediated by site-2 protease, but not site-1 protease. Plant J, 91, 408-15.
  17. Asahi Shimada, Azusa Okumura, Satoshi Yamasaki, Yuji Iwata, Nozomu Koizumi, Masahiro Nishihara, Kei-ichiro Mishiba (2017) A 64-bp sequence containing the GAAGA motif is essential for CaMV-35S promoter methylation in gentian. Biochim Biophys Acta, 1860, 861-9.
  18. Riko Tanaka, Makoto Amijima, Yuji Iwata, Koizumi, Kei-ichiro Mishiba (2016) Effect of light and auxin transport inhibitors on endoreduplication in hypocotyl and cotyledon. Plant Cell Rep, 35, 2539-47.
  19. Yuji Iwata, Noriko Hayashi, Kazuki Tabara, Kei-ichiro Mishiba, Nozomu Koizumi (2016) Tunicamycin-induced inhibition of protein secretion into culture medium of Arabidopsis T87 suspension cells through mRNA degradation on the endoplasmic reticulum. Biosci Biotechnol Biochem, 80, 1168-71.
  20. Yukihiro Nagashima, Yuji Iwata, Kei-ichiro Mishiba, Nozomu Koizumi (2016) Arabidopsis tRNA ligase completes the cytoplasmic splicing of bZIP60 mRNA in the unfolded protein response. Biochem Biophys Res Commun 470, 941-6.
  21. Azusa Okumura, Asahi Shimada, Satoshi Yamasaki, Takuya Horino, Yuji Iwata, Nozomu Koizumi, Masahiro Nishihara, Kei-ichiro Mishiba (2016) CaMV-35S promoter sequence- specific DNA methylation in lettuce. Plant Cell Rep 35: 43-51.
  22. Makoto Amijima, Yuji Iwata, Nozomu Koizumi, Kei-ichiro Mishiba (2014) The polar auxin transport inhibitor TIBA inhibits endoreduplication in dark grown spinach hypocotyls. Plant Sci, 225, 45-51.
  23. Yukihiro Nagashima, Yuji Iwata, Makoto Ashida, Kei-ichiro Mishiba, Nozomu Koizumi (2014) Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis. Plant Cell Physiol, 55, 1772-1778, 2014.
  24. Yosuke Miyagawa, Jun Ogawa, Yuji Iwata, Nozomu Koizumi, Kei-ichiro Mishiba (2013) An attempt to detect siRNA-mediated genomic DNA modification by artificially induced mismatch siRNA in Arabidopsis. PLoS ONE 8, e81326-1-7.
  25. Kei-ichiro Mishiba, Yukihiro Nagashima, Eiji Suzuki, Noriko Hayashi, Yoshiyuki Ogata, Yukihisa Shimada, Nozomu Koizumi (2013) Defects in IRE1 enhance cell death and fail to degrade mRNAs encoding secretory pathway proteins in the Arabidopsis unfolded protein response. Proc Natl Acad Sci USA 110, 5713-5718
  26. Yuji Iwata, Masateru Takahashi, Nina V Fedoroff, Samir M Hamdan (2013) Dissecting the interactions of SERRATE with RNA and DICER-LIKE 1 in Arabidopsis microRNA precursor processing. Nucleic Acids Res 41, 9129-9140
  27. Yuji Iwata, Tsuneyo Nishino, Megumi Iwano, Seiji Takayama, Nozomu Koizumi (2012) Role of the plant-specific endoplasmic reticulum stress-inducible gene TIN1 in the formation of the pollen surface structure in Arabidopsis thaliana. Plant Biotechnol 28, 51-56
  28. Yukihiro Nagashima, Kei-ichiro Mishiba, Eiji Suzuki, Yukihisa Shimada, Yuji Iwata, Nozomu Koizumi (2011) Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor. Sci Rep 1, 29
  29. Yuji Tanaka, Shinya Nakamura, Makoto Kawamukai, Nozomu Koizumi, Tsuyoshi Nakagawa (2011) Development of series of gateway binary vectors possessing a tunicamycin resistance gene as a marker for transformation of Arabidopsis thaliana. Biosci Biotechnol Biochem 75:804-807
  30. Satoshi Yamasaki, Masayuki Oda, Nozomu Koizumi, Kazuhiko Mitsukuri, Masafumi Johkan, Takashi Nakatsuka, Masahiro Nishihara, Kei-ichiro Mishiba (2011) De novo DNA methylation of the 35S enhancer revealed by high-resolution methylation analysis of an entire T-DNA segment in transgenic gentian. Plant Biotechnol 28:223-230
  31. Yuji Iwata, Tsuneyo Nishino, Seiji Takayama, Nozomu Koizumi (2010) Characterization of a plant-specific gene induced by endoplasmic reticulum stress in Arabidopsis thaliana. Biosci Biotechnol Biochem 74, 2087-2091.
  32. Yuji Iwata, Masayo Sakiyama, Mi-Hyun Lee, Nozomu Koizumi (2010) Transcriptomic response of Arabidopsis thaliana to tunicamycin-induced endoplasmic reticulum stress. Plant Biotechnol 27, 161-171
  33. Yuji Iwata, Mari Yoneda, Yuki Yanagawa, Nozomu Koizumi (2009) Characteristics of the nuclear form of the Arabidopsis transcription factor AtbZIP60 during the endoplasmic reticulum stress response. Biosci Biotechnol Biochem 73, 865-869
  34. Iwata, Y., Fedoroff, N. V., & Koizumi, N. (2009). The Arabidopsis membrane-bound transcription factor AtbZIP60 is a novel plant-specific endoplasmic reticulum stress transducer. Plant Signaling and Behavior, 4, 514-516.
  35. Yuji Iwata, Nina V Fedoroff, Nozomu Koizumi (2008) Arabidopsis bZIP60 is a proteolysis-activated transcription factor involved in the endoplasmic reticulum stress response. Plant Cell 20, 3107-3121
  36. Nozomu Koizumi, Yuji Iwata (2008) Construction of a binary vector for transformation of Arabidopsis thaliana with a new selection marker. Biosci Biotechnol Biochem 72, 3041-3043
  37. Hiromi Tajima, Yuji Iwata, Megumi Iwano, Seiji Takayama, Nozomu Koizumi (2008) Identification of an Arabidopsis transmembrane bZIP transcription factor involved in the endoplasmic reticulum stress response. Biochem Biophys Res Commun 374, 242-247
  38. Yuji Iwata, Takeo Yamada, Nozomu Koizumi (2008) Transcriptional regulation of an Arabidopsis gene encoding a CCT domain-containing protein during endoplasmic reticulum stress. Plant Biotechnol 25, 397-402
  39. Tateda, C., Ozaki, R., Onodera, Y., Takahashi, Y., Yamaguchi, K., Berberich, T., Koizumi N., & Kusano T. (2008). NtbZIP60, an endoplasmic reticulum-localized transcription factor, plays a role in the defense response against bacterial pathogens in tobacco. Journal of Plant Research, 121, 603-611.
  40. Akaboshi, M., Hashimoto, H., Ishida, H., Saijo, S., Koizumi, N., Sato, M., et al. (2008). The crystal structure of plant-specific calcium-binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14. Journal of Molecular Biology, 377, 246-257.
  41. Lee, E.J., Matsumura, Y., Soga, K., Hoson, T., & Koizumi, N. (2007). Glycosyl hydrolases of cell wall are induced by sugar starvation in Arabidopsis. Plant and Cell Physiology, 48, 405-413.

 

【総説等】

  1. 小泉望 (2024) ゲノム編集食品をどう伝えるか：生活協同組合研究．p577, 34-41
  2. 小泉望、四方雅仁（2022）ゲノム編集食品の取り扱いに関するルール. 化学と生物，60，150-153 [Link]
  3. Rengin Ozgur, Baris Uzilday, Yuji Iwata, Nozomu Koizumi, Ismail Turkan (2018) Interplay between the unfolded protein response and reactive oxygen species: a dynamic duo. J Exp Bot 69:3333–3345 [PubMed]
  4. 岩田雄二，小泉望 (2018) 植物における膜結合型転写因子の活性化機構―膜に結合している転写因子が核に移行する2つの仕組み―．化学と生物 56巻11号 732-737ページ
  5. 小泉望（2015）国内外における遺伝子組換え作物の状況． 植調 48(12), 477-481
  6. 小泉望（2015）閉鎖型植物工場における遺伝子組換え植物栽培の現状と今後．　機能材料 Vol. 35 No.1, 58-60
  7. 小泉望、長島幸広（2013）生物間における細胞質スプライシングの保存性と多様性．　生化学 85(6), 1095－1099
  8. 小泉望（2013）「食品表示について考える」　近畿化学工業会　65(9), 7-10
  9. Yuji Iwata and Nozomu Koizumi (2012) Plant transducers of the endoplasmic reticulum unfolded protein response. Trends Plant Sci17, 720-727
  10. 小泉望 (2012) 遺伝子組換え植物をめぐる国内外の状況．月刊バイオインダストリー 29(8):5-11ページ[LINK]
  11. Yuji Iwata, Mi-Hyun Lee, Nozomu Koizumi (2011) Analysis of a transcription factor using transient assay in Arabidopsis protoplasts. Methods Mol Biol 754, 107-17
  12. 小泉望, 岩田雄二 (2011) 植物における小胞体タンパク質品質管理―病原菌認識機構の解析から見えて来たもの―. 化学と生物 49巻2号 88-93ページ
  13. 小泉望、中山祐一郎 (2010) 遺伝子組換え（GM）ナタネのこぼれ種と生物多様性． バイオサイエンスとインダストリー　Vol.68 No.5, 361-363
  14. 小泉望（2009） 「遺伝子組換え作物」を社会にどう伝えるか　－科学と社会のかかわりのなかで． 化学, 64 (8), 12-15.
  15. Yuji Iwata*, Nina V. Fedoroff, Nozomu Koizumi (2009) The Arabidopsis membrane-bound transcription factor AtbZIP60 is a novel plant-specific endoplasmic reticulum stress transducer. Plant Signal Behav 4, 514-516 (*corresponding author)
  16. Hiromi Tajima, Yuji Iwata, Nozomu Koizumi (2008) Endoplasmic reticulum stress response and regulated intramembrane proteolysis in plants. Plant Biotechnol 25, 271-278
  17. 小泉望（2008） 遺伝子組換え作物に関する最近の動向．作物研究, 53, 3-6

 

【著書】

  1. 小泉望、四方雅人（2023）　ゲノム編集食品に関する取扱いルールの経緯とこれから：ゲノム編集技術を応用した製品開発とその実用化．p565-572　技術情報協会
  2. 小泉　望（2023）リスクコミュニケーションのために求められること：ゲノム編集技術 ～実験上のポイント／産業利用に向けた研究開発動向と安全性周知　p295-p301　情報機構  [Link]
  3. 小泉　望（2022）植物バイオテクノロジーでめざすSDGs（編著）ｐ163-167　化学同人 [Link]
  4. 小泉　望、山口　夕、標葉隆馬 （2022）OECD加盟国におけるゲノム編集作物に関するパブリック・エンゲージメント事例集、科学コミュニケーション研究所 [Link]
  5. Kazuki Tabara, Yuji Iwata, Nozomu Koizumi (2018) The Unfolded Protein Response. In: Chris Hawes, Verena Kriechbaumer Eds., The Plant Endoplasmic Reticulum, Methods and Protocols, Springer, pp 223-230 [Springer Link]
  6. Yuji Iwata and Nozomu Koizumi (2015) Membrane-bound transcription factors in plants: physiological roles and mechanisms of action. In: Daniel H Gonzalez (ed) Plant Transcription Factors: evolutionary, Structural and Functional Aspects. Elsevier, pp 385-394.
  7. 小泉　望 （2015） 遺伝子組み換え作物とは何か？：誤解だらけの遺伝子組み換え作物、小島正美編、p51-64、 エネルギーフォーラム 
  8. 小泉　望 （2015） 植物に適用した遺伝子組換え技術のこれまでと今後：進化するゲノム編集技術、監修　真下　知士、城石　俊彦、pp311-319、エヌ・ティー・エス [Link]
  9. Mishiba, K., Nagashima, Y., Hayashi, N., & Koizumi, N. (2014). DNA fragmentation analysis. Bio-protocol, 4(15), e1203. [Link]
  10. 「書評：椎名隆、石崎陽子監訳　有機農業と遺伝子組換え食品」(2011)　學鐙、第109巻 第1号、54-55頁、丸善
  11. Iwata, Y., Lee, M.H., & Koizumi, N. (2011) Analysis of a transcription factor using transient assay in Arabidopsis protoplasts. In Yuan, Ling; Perry, Sharyn E. (Eds.) Methods in Molecular Biology, vol. 754, pp107-117, Humana Press
  12. 「救え！世界の食糧危機　ここまできた遺伝子組換え作物」（2009）日本学術振興会・植物バイオ第160委員会監修、化学同人　（分担執筆）
  13. 「植物で未来をつくる」(2008)　松永和紀著/日本植物生理学会監修、化学同人 （分担執筆）