About Us

Everything around us is ultimately composed of nanoscale building blocks such as molecules and ions. If these fundamental components could be precisely manipulated at will, they would open new possibilities for revolutionary medical technologies, environmental solutions, and next-generation energy systems. However, observing individual molecules and ions in solution, manipulating them at intended locations, in defined sequences, and at precise timings, controlling their behavior and reactions, and ultimately creating new materials from them have long remained one of the greatest challenges in science and engineering.

Our laboratory develops new principles and technologies that enable the precise transport, analysis, manipulation, control, synthesis, and separation of molecules, ions, and nanomaterials in solution using nanofluidic devices with nanometer-scale confined spaces as our core technological platform. By systematizing these advances, we are creating a new interdisciplinary field, Nano Chemical Systems Engineering, which integrates nanotechnology, chemistry, and systems engineering at the molecular scale. Building upon this new academic discipline, we have pioneered the concepts of Single-Molecule Regulated Chemistry (SMRC)— a new paradigm of chemistry in which chemical processes can be rationally designed and precisely controlled at the single-molecule level—and its engineering counterpart, Single-Molecule-Regulated Chemical Engineering (SMRChE). We are now working toward establishing these concepts as a new scientific and engineering framework.

Our research spans a broad range of targets, including small molecules, biomolecules (such as DNA and proteins), exosomes, viruses, nanoparticles, quantum dots, and two-dimensional materials. It also brings together a broad spectrum of disciplines, including chemical engineering, fundamental chemistry, analytical chemistry, materials science, nanomedicine, neuroscience, synthetic biology, engineering biology, photonics, quantum science, information science, and data science (AI and big data).

Our ultimate vision is to create new scientific principles and future technologies that enable the rational design and precise control of molecules, ions, and nanomaterials. Through these advances, we aspire to contribute to solving global challenges, including ultra-early disease diagnosis, next-generation drug discovery, environmental remediation, energy-efficient technologies, and the realization of a sustainable society.

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Research Fields : Nanofluidics, Nano Chemical Systems, Microfluidics, NanoBio Interfaces, Analytical Chemistry, Biomaterials, Nanomedicine, Single-Molecule Chemistry, Single-Cell Omics, Nano Energy
Featured Keywords : Nano-in-Nano Integration, Digital Nanochannels (DN), Single-Molecule Regulated Chemistry (SMRC), Single-Molecule-Regulated Chemical Engineering (SMRChE)
Other Keywords : Nanochannels, Nanofluidic Channels, Nanofluidic Devices (Chips), Two-Dimensional (2D) Materials, 2D Nanofluidic Membranes, Microchannels, Microfluidic Channels, Microfluidic Devices (Chips) Lab on a Chip, MicroTAS, Single Molecule, Single Cell

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