Publications
Scientific Articles
2026
- Biosensing with nanofluidics
Qun Ma., Yan Xu
Exploration, 2026, in press.
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- Molecular Permeability Behavior and Catalytic Effectiveness in Zwitterionic Polymer Hydrogel-Enzyme Hybrid Nanocarrier
Xuejin Huang, Jincai Li, Nattapong Chantipmanee, Yusuke Dote, Yan Xu, Madoka Takai
Biomacromolecules, 2026, 27, 1857−1866.
(doi: 10.1021/acs.biomac.5c01738)[PDF]
(Featured on the cover of the journal; Biomacromolecules , Vol. 27, Issue 3, 2026 [ PDF ] )
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- Nanopore Sensing: Current Progress and Future Challenges Tackled by Nanofluidic Devices
Wachara Chanakul, Nattapong Chantipmanee, Matthieu Sandell, Rebecca An, Michael Mayer, Yan Xu
TrAC Trends in Analytical Chemistry, 2026, 194, 118541.
(doi: 10.1016/j.trac.2025.118541)[PDF]
(Japanese press release by OMU website, OMU X, OMU Facebook . Main text of the press release.
maintext link: https://www.omu.ac.jp/assets/attachmentfile/attachmentfile-file-84984.pdf(Overseas press release by OMU English website, EurekAlert!, OMU X (English ), OMU Facebook (English) .(Featured on overseas media: Phys.org, Longbridge, Statnano, Gate2Biotech, RNA-Seq Blog, etc.
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2025
- Nanofluidic devices for single-molecule analytical chemistry
Qun Ma., Yan Xu
Analytical Sciences, 2025, 41, 1289-1304.
(doi: 10.1007/s44211-025-00801-0) [PDF]
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- Clay-Based Nanofluidic Membrane with Enhanced Space Charge for Robust Osmotic Energy Harvesting
Qijun Zheng, Yue Shen, Lina Wang, Jin Wang, Hanjun Sun, Yan Xu, Chen Wang
ACS Applied Materials & Interfaces, 2025, 17, 20, 29469–29477
(doi: 10.1021/acsami.4c20210) [PDF]
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- Two-Sided Asymmetric Nanofluidic Membrane for Enhanced Ion Transport and Osmotic Energy Harvesting
Qijun Zheng, Yue Shen, Junjian Lu, Yan Xu, Xing-Hua Xia, Chen Wang
Chemical Science, 2025, in press.
(doi: 10.1039/D5SC01237F) [PDF]
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- Microfluidic-Enabled Self-Directed Hydrogel Microspheres for Multiplexed MicroRNA Assays
Yongning Lin, Gaowa Xing, Zengnan Wu, Jin-Ming Lin, Jiaxu Lin, Ying Hou, Yajing Zheng, Yan Xu, Ling Lin
Analytical Chemistry, 2025, 97, 4, 1972−1976.
(doi: 10.1021/acs.analchem.4c05349) [PDF]
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2024
- Nanofluidic Manipulation of Single Nanometric Objects: Current Progress, Challenges, and Future Opportunities
Nattapong Chantipmanee, Yan Xu
Engineering, 2024, 43, 54-71.
(doi:10.1016/j.eng.2024.08.021) [PDF]
(Press release in OMU X & OMU Facebook, OMU English website , EurekAlert! , Alpha Galileo , Asia Research News)
( Featured on overseas media : Phys.org , Azonano etc.)
(Featured on the cover of the journal)
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- Enzyme stability in polymer hydrogel-enzyme hybrid nanocarrier containing phosphorylcholine group
Xuejin Huang, Jincai Li, Yasuyuki Araki, Takehiko Wada, Yan Xu, Madoka Takai
RSC Advances, 2024,14, 18807-18814.
(doi:10.1039/d4ra02436b) [PDF] [SI]
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- ナノ流体デバイスを基盤とするナノ化学システム工学の創成
許岩
化学とマイクロ・ナノシステム, 2024,23, 2, 10-11.
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2023
- A simple chemical method to nondestructively regenerate functional nanochannels for single-molecule studies
Jinbin Yang, Hiroki Kamai, Yan Xu
Sensors and Actuators B: Chemical, 2023, 393, 134106. (doi:10.1016/j.snb.2023.134106) [PDF] [SI]
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- Nanofluidic aptamer nanoarray to enable stochastic capture of single proteins at normal concentrations
Jinbin Yang, Hiroki Kamai, Yong Wang, Yan Xu
Small, 2023, 19, 2301013. (doi:10.1002/smll.202301013) [PDF] [SI]
(Featured on the Frontispiece of the journal)
(Japanese press release byOMU.Main textof the press release;).
( Overseas press release by OMU English website , EurekAlert! , Alpha Galileo , Asia Research News , OMU Facebook (English) , OMU Twitter(English )( Featured on overseas media : GEN (Genetic Engineering & Biotechnology News) , Astrobiology Web , Drug Target Review , The Medical News , Labiotech , Phys.Org , Azonano , Mirage News , ScienMag , Nanowerk , Bioengineer.org , NewsBeezer , Samachar Central , megafea , Swift Telecast , Glory Glob Tv , Nouvelles du monde , AskByGeeks , Dispositivos Medicos , Ma Clinique , Euro ES Euro , My Droll , AskByGeeks , Deporticos , PlatoHealth , Zephyrnet , etc.)( Featured on Japanese media: NIKKEI Tech Foresight )( Featured on Chinese media : Chemistry and Materials Science , etc.)
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- Flexible glass-based hybrid nanofluidic device to enable the active regulation of single-molecule flows
Hiroto Kawagishi, Shun-ichi Funano, Yo Tanaka, Yan Xu
Nano Letters, 2023, 23, 2210-2218. (doi:10.1021/acs.nanolett. 2c04807) [PDF] [SI] [Supplementary Movie 1] [Supplementary Movie 2] [Supplementary Movie 3]
(Click here (YouTubeclip 1,clip 2) to watch video clips related to this study)
( Joint press release in Japanese by OMU and RIKEN . Main text of the press release; OMU Facebook , OMU Twitter ).
( Overseas press release by OMU English website , EurekAlert! , Alpha Galileo , Asia Research News , OMU Facebook , OMU Twitter ) ( Featured on Japanese media: OPTRONICS ONLINE , NIKKEI Tech Foresight , Nikkei Crosstech (Nikkei xTECH) , Nikkan Chemical News ) ( Featured on overseas media : Official Twitter of Nano Letters , AZO Materials , LABIOTECH , Science Daily , Bioengineer.org , ScienMag , Nanowerk , Mirage News , Today Headline , SciTechDaily , Bollyinside , Nano Daily , list23 , etc.) ( Featured on Chinese media : Sohu , ScienceNet , antpedia , Alpatent , etc.)
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- Toward nanofluidics-based mass spectrometry for exploring the unknown complex and heterogenous subcellular worlds (invited)
Nattapong Chantipmanee, Yan Xu
View, 2023, 4, 20220036. (doi:10.1002/VIW.20220036) [PDF]
(Featured on the cover of the journal; View , 2023, 4, e268 [ PDF ] )
(Featured on the Chinese online scientific media "Frontal Experiential Doctor" )
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- Nanofluidics for chemical and biological dynamics in solution at the single molecular level (invited)
Nattapong Chantipmanee, Yan Xu
TrAC Trends in Analytical Chemistry, 2023, 158, 116877. (doi:10.1016/j.trac.2022.116877) [PDF]
(Press release in Japanese byOMU.Main textof the press release . OMU Twitter & OMU Facebook ) (Press release in English by OMU English website , EurekAlert! , Alpha Galileo , Asia Research News , OMU Facebook , OMU Twitter ) ( Featured on overseas media : Phys.org , Mirage News , AZoM , Analytica World , analytica-world.com , Bioengineer.org , Innovations Report , Nanowerk , ScienceDaily , Knowledia , ChemEurope , Verve Times , News Concern etc.
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- (Book Chapter) Nanofluidic Technologies for Drug Screening and Drug Delivery (invited)
Yutaka Kazoe, Kenji Sueyoshi, Sakikarn Seetasang, Yan Xu
in “Nano- and Microfabrication Techniques in Drug Delivery: Recent Developments and Future Prospects”,Springer Nature, April. 2023. (doi: 10.1007/978-3-031-26908-0_14)
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- １分子バルブとその光信号増強効果
川岸啓人，許岩
光アライアンス, 2023, 34, 10, 10-14.
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- ナノ流体デバイスが拓く１分子制御化学プロセス
川岸啓人，許岩
ながれ, 2023, 42, 237-242.[PDF]
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- 先端的分析化学のためのナノ流体デバイスの作製技術
小林丈，許岩
ぶんせき, 2023, 2, 57-58.[PDF]
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2022
- Nanofluidics for sub-single cellular studies: nascent progress, critical technologies, and future perspectives (invited)
Jinbin Yang, Yan Xu
Chinese Chemical Letters (CCL), 2022, 33, 2799-2806. (doi:10.1016/j.cclet.2021.09 .066) [PDF]
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- Recent progress and perspectives in applications of 2-methacryloyloxyethyl phosphorylcholine polymers in biodevices at small scales (Invited)
Sasikarn Seetasang, Yan Xu
Journal of Materials Chemistry B, 2022, 10, 2323-2337. (doi:10.1039/D1TB02675E) [PDF].
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- A biomimetic anti-biofouling coating in nanofluidic channels
Sumire Fukuda, Yan Xu
Journal of Materials Chemistry B, 2022, 10, 2481-2489. (doi:10.1039/D1TB02627E) [PDF] [ESI]
( Selected as HOT Paper)
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- 1分子FRETと2-color二次元蛍光寿命相関分光法による核酸のマイクロ秒構造変化ダイナミクスの検出
田中優仁，許岩
ぶんせき, 2022, 7, 261.
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2021
- Fabrication of nanoscale gas-liquid interfaces in hydrophilic/hydrophobic nanopatterned nanofluidic channels
Hiroto Kawagishi, Shuichi Kawamata, Yan Xu
Nano Letters, 2021, 21, 10555-10561. (doi:10.1021/acs.nanolett.1c02871) [PDF] [SI]
(Featured on the cover of the journal )
( Click here ( YouTube ) to watch a movie clip for this study )
( Joint press release by OPU and JST . Main text of the press release )
( Featured on Japanese media: NIKKAN KOGYO SHIMBUN )
( Featured on overseas media : OPU , OMU , EurekAlert!, Asia Research News , Phys.org , Nanowerk , Chem Europe , ScienMag , True Viral News , Mirage , Official Twitter of Nano Letters , FUNTiTECH , Xnesnet , etc.) ( Featured on Chinese media : NetEase , Sohu , Zhihu Science & Technology, Baidu Zhidao , Official Wechat site of Chemistry & Material Sciences )
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- (Book Chapter) Nano-in-Nano Integration Technology for Advanced Fabrication of Functional Nanofluidic Devices
Jinbin Yang, Yan Xu
in “Advanced MEMS/NEMS Fabrication and Sensors”,pp111-132, Springer Nature, 2021. (doi:10.1007/978-3-030-79749-2_5)
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- (Book Chapter) Principles and applications of the nano-in-nano integration for multidisciplinary nanofluidics
Jinbin Yang, Yan Xu
in “Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip: Principles and Applications”,pp407-428, Elsevier, 2021. (doi:10.1016/B978-0-444-59432-7.00012-1)
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- Fabrication of Ultranarrow Nanochannels with Ultrasmall Nanocomponents in Glass Substrates
Hiroki Kamai, Yan Xu
Micromachines, 2021, 12(7), 775. (doi:10.3390/mi12070775) [PDF].
(Open Access)
( Selected as Editor's Choice &. Feature Paper)
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- (Editorial) Advances in Nanofluidics
Yutaka Kazoe, Yan Xu
Micromachines, 2021, 12(4), 427. (doi:10.3390/mi12040427) [PDF].
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- Correction: Microfluidic flow control on charged phospholipid polymer interface
Yan Xu, Madoka Takai, Tomohiro Konno, Kazuhiko Ishiharai
Lab on a Chip, 2021, 21, 976-976. (doi:10.1039/D1LC90013G)[PDF] [Original Paper]
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- (Book Chapter) Some frontier technologies for aptamers in medical applications
Yiyang Dong, Sai Wang, Lianhui Zhao, Jinbin Yang, Yan Xu
in'Aptamers for Medical Applications. From Diagnosis to Therapeutics' , pp375-403, Springer Nature, 2021. (doi:10.1007/978-981-33-4838-7_13)
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- (Book Chapter) Functional coatings for lab-on-a-chip systems based on phospholipid polymers
Yan Xu, Madoka Takai, Kazuhiko Ishihara
in'Handbook of Modern Coating Technologies. Applications and Development' , pp555-595, Elsevier, 2021. (doi:10.1016/b978-0-444-63237-1.00016-4)
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- 細胞外小胞の単離，分析技術の現状とナノ流体デバイスがもたらす新戦略
村田幸作，許岩
実験医学, 2021, 39, 20, 170-177 (3280-3287).
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2020
- (Book Chapter) Beyond Phenomena: Functionalization of Nanofluidics Based on Nano-in-Nano Integration Technology
Yan Xu
in '21st Century Nanoscience - A Handbook, Exotic Nanostructures and Quantum Systems (Volume Five)' , pp13-1~13-18, Taylor & Francis (CRC Press), 2020.
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- Generation of nanometer-scale geometrical gas-liquid interfaces in hydrophilic/hydrophobic patterned nanochannels
Hiroto Kawagishi, Shuichi Kawamata, Yan Xu
Proceedings of Micro Total Analysis Systems , 2020, 190-191.
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- Aptamer-based nanofluidics for the molecular detection in ultra-small volume
Jinbin Yang, Hiroki Kamai, Yong Wang, Yan Xu
Proceedings of Micro Total Analysis Systems , 2020, 354-355.
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- Fabrication of sub-40-nanometer nano-in-nano structures in nanochannels
Hiroki Kamai, Yan Xu
Proceedings of Micro Total Analysis Systems , 2020, 366-367.
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- 1分子制御化学に向けたアトリットル液滴のアレイ化と混合
川岸啓人, 許岩
化学とマイクロ・ナノシステム, 2020, 19, 1, 29-30.
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2019
- Fabrication and evaluation of flexible nanovalves in 2D-nanochannels
Hiroto Kawagishi, Shun-ichi Funano, Yo Tanaka, Shuichi Kawamata and Yan Xu
Proceedings of Micro Total Analysis Systems , 2019, 1182-1183.
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- ナノ流体デバイスと光圧技術を融合した1分子DNA操作
佐々木雄太，西岡賢史，島谷雄士，許岩
化学とマイクロ・ナノシステム, 2019, 18, 2,41-42.
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2018
- (Inside Back Cover) Nanofluidics: Nanofluidics: a New Arena for Materials Science (Adv. Mater. 3/2018)
Yan Xu
Advanced Materials, 2018, 30, 1870019. (doi:10.1002/adma.201870019) [PDF]
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- Nanofluidics: a New Arena for Materials Science (invited)
Yan Xu
Advanced Materials, 2018, 30, 1702419. (doi:10.1002/adma.201702419) [PDF]
(Featured on the inside back cover of the journal)
(2nd place among Top ten hot papers/Top ten most accessed papers of Advanced Materials, November, 2017)
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2017
- Bridging world-to-nanofluidics interfaces through nano-in-nano integration technology
Yan Xu
IEEE MHS, 2016, 16603900, 159-160. (doi:0.1109/MHS.2016.7824225)
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2016
- Soft Matter-Regulated Active Nanovalves Locally Self-Assembled in Femtoliter Nanofluidic Channels
Yan Xu, Misato Shinomiya, Atsushi Harada
Advanced Materials, 2016, 28, 2209-2216. (doi:10.1002/adma.201505132) [PDF] [SI]
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- Antifouling surface modification of nanochannels using a silanized phospholipid monomer
Qian Wu, Yan Xu
Proceedings of Micro Total Analysis Systems , 2016, 1152-1153.
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- １兆分の1 mLの水を自在に制御できる技術 (A Technique Enabling the Active Regulation of Femtoliter-Scale Liquids)
許 岩 (Yan Xu)
自動車技術 （「超の世界」） (Journal of Society of Automotive Engineers of Japan), 2016, 70 (9), 122-123.
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- ナノ流路で開閉可能な超微小スマートバルブ──フェムトリットル単位の液体を自在に制御
許 岩，原田 敦史
化学, 2016, 71 (7), 36-39.
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- リン脂質ポリマーハイドロゲルを用いたOn-Chip細胞保存（On-Chip Cell Preservation by Using a Phospholipid Polymer Hydrogel)
許 岩 (Yan Xu)
色材協会誌（Journal of the Japan Society of colour Material）, 2016, 89(5), 154-158.
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2015
- Spontaneous Packaging and Hypothermic Storage of Mammalian Cells with a Cell-Membrane-Mimetic Polymer Hydrogel in a Microchip
Yan Xu, Kazuma Mawatari, Tomohiro Konno, Takehiko Kitamori, Kazuhiko Ishihara
ACS Applied Materials & Interfaces, 2015, 7, 23089-23097. (doi:10.1021/acsami.5b06796)[PDF] [SI]
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- (Inside Cover) Nanochannels: An Integrated Glass Nanofluidic Device Enabling in situ Electrokinetic Probing of Water Confined in a Single Nanochannel under Pressure-Driven Flow Conditions
Yan Xu, Baihui Xu
Small, 2015, 11, 6110.(doi:10.1002/smll.201570275) [PDF]
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- An Integrated Glass Nanofluidic Device Enabling in situ Electrokinetic Probing of Water Confined in a Single Nanochannel under Pressure-Driven Flow Conditions
Yan Xu, Baihui Xu
Small, 2015, 11, 6165-6171.(doi:10.1002/smll.201502125) [PDF]
(Selected as VIP ) ( Featured on the inside front cover of the journal )
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- (Back Cover) Regeneration of Glass Nanofluidic Chips through a Multiple-Step Sequential Thermochemical Decomposition Process at High Temperatures
Yan Xu, Qian Wu, Yuji Shimatani, Koji Yamaguchi
Lab on a Chip, 2015, 15, 3953. (doi:10.1039/C5LC90105G)[PDF]
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- Regeneration of Glass Nanofluidic Chips through a Multiple-Step Sequential Thermochemical Decomposition Process at High Temperatures
Yan Xu, Qian Wu, Yuji Shimatani, Koji Yamaguchi
Lab on a Chip, 2015, 15, 3856-3861. (doi:10.1039/C5LC00604J)[PDF] [ESI]
(Open Access)
( Featured on the back cover of the journal )
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- Flexible and in situ fabrication of nanochannels with high aspect ratios and nanopillar arrays in fused silica substrates utilizing focused ion beam
Yan Xu, Nobuhiro Matsumoto
RSC Advances , 2015, 5, 50638-50643. (doi: 10.1039/C5RA06306J)[ PDF ] [ ESI ]
( Open Access )
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- (Back Cover) Site-Specific Nanopatterning of Functional Metallic and Molecular Arbitrary Features in Nanofluidic Channels
Yan Xu, Nobuhiro Matsumoto, Qian Wu, Yuji Shimatani, Hiroaki Kawata
Lab on a Chip, 2015, 15, 2147. (doi: 10.1039/C5LC90053K) [PDF]
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- Site-Specific Nanopatterning of Functional Metallic and Molecular Arbitrary Features in Nanofluidic Channels
Yan Xu, Nobuhiro Matsumoto, Qian Wu, Yuji Shimatani, Hiroaki Kawata
Lab on a Chip, 2015, 15, 1989-1993. (doi: 10.1039/C5LC00190K) [PDF] [ESI]
(Open Access)
(Featured on the back cover of the journal doi: 10.1039/ C5LC90053K
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2014
- Determination of cattle foot-and-mouth disease virus by micro-ELISA method
Yiyang Dong, Yan Xu, Zaixin Liu, Yuanfang Fu, Toshinori Ohashi, Kazuma Mawatari, Takehiko Kitamori
Analytical Sciences, 2014, 30, 359-363. (doi:10.2116/analsci.30.359) [PDF]
(Selected as a "Hot Article")
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- Aptamers and their potential applications for food safety
Yiyang Dong, Yan Xu, Wei Yong, Xiaogang Chu, Daning Wang
Critical Reviews in Food Science and Nutrition, 2014, 54, 1548-1561. (doi:10.1080/10408398.2011.642905) [PDF]
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- マイクロ・ナノ空間の機能化表面・界面の構築と制御
許岩
化学とマイクロ・ナノシステム, 2014,13, 2, 20.
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- Design, synthesis and characterization of a thiolated temperature-responsive polymer for smart nanofluidic control
Misato Shinomiya, Atsushi Harada, Yan Xu
Proceedings of Micro Total Analysis Systems , 2014, 1841-1843.[ PDF ]
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2013
- Bonding of glass nanofluidic chips at room temperature by a one-step surface activation using an O2/CF4 plasma treatment
Yan Xu, Chenxi Wang, Lixiao Li, Nobuhiro Matsumoto, Kihoon Jang, Yiyang Dong, Kazuma Mawatari, Tadatomo Suga, Takehiko Kitamori
Lab on a Chip, 2013, 13, 1048-1052. (doi:10.1039/C3LC41345D) [PDF] [ESI]
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- Arbitrary nanopatterning inside nanochannels by integration of top-down and bottom-up approaches for single molecule analysis
Nobuhiro Matsumoto, Yan Xu
Proceedings of Micro Total Analysis Systems , 2013, 119-121.[ PDF ]
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2012
- (Book Chapter) Modification of Glass Substrates and Microfluidic Devices by Silanization of Bioinspired 2-Methacryloyloxyethyl Phosphorylcholine (MPC) Polymers for Preparing Biocompatible Interfaces
Yan Xu, Madoka Takai, Kazuhiko Ishihara'Silane: Chemistry, Applications and Performance', Edited by Katsuo Moriguchi and Susumu Utagawa, Nova Science Publishers (2012).
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- Femtoliter droplet handling in nanofluidic channels: a Laplace nanovalve
Kazuma Mawatari, Shogo Kubota, Yan Xu, Craig Priest, Rossen Sedev, John Ralston, Takehiko Kitamori
Analytical Chemistry , 2012, 84, 10812-10816. (doi: 10.1021/ac3028905) [PDF]
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- 生体親和性ポリマーを用いた細胞チップの開発(Development of cell chips based on biocompatible polymers)
許 岩, 張 氣薫, 北森 武彦 (Yan Xu, Kihoon Jang, Takehiko Kitamori)
バイオマテリアル-生体材料-(Journal of Japanese Society for Biomaterials), 2012, 30-3, 159-167.
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- Micropatterning of biomolecules on a glass substrate in fused silica microchannels by using photolabile linker-based surface activation
Kihoon Jang, Yan Xu, Kae Sato, Yo Tanaka, Kazuma Mawatari, Takehiko Kitamori
Microchimica Acta , 2012, 179, 49-55. (doi:10.1007/s00604-012-0856-8) [PDF]
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- Low-temperature direct bonding of glass nanofluidic chips using a two-step plasma surface activation process
Yan Xu, Chenxi Wang, Yiyang Dong, Lixiao Li, Kihoon Jang, Kazuma Mawatari, Tadatomo Suga, Takehiko Kitamori
Analytical and Bioanalytical Chemistry , 2012, 402, 1011-1018. (doi:10.1007/s00216-011-5574-2) [PDF]
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- Microchip-based cellular biochemical systems for practical applications and fundamental research: from microfluidics to nanofluidics
Yan Xu, Kihoon Jang, Tadahiro Yamashita, Yo Tanaka, Kazuma Mawatari, Takehiko Kitamori
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Analytical and Bioanalytical Chemistry , 2012, 402, 99-107. (DOI: 10.1007/s00216-011-5296-5) [ PDF ]
- (Book Chapter) Cytocompatible hydrogel composed of phospholipid polymers for regulation of cell functions
Kazuhiko Ishihara, Yan Xu, Tomohiro Konnoin'Polymers in Nanomedicine', Edited by Shigeru Kunugi, Springer Berlin/Heidelberg, ,inAdvances in Polymer Science,2012, 247, 147-165. (DOI: 10.1007/12_2011_151) [PDF]
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- A room-temperature bonding of glass nanofluidic chips utilizing a surface activation with a fluorine-containing plasma treatment
Yan Xu, Chenxi Wang, Kihoon Jang, Lixiao Li, Nobuhiro Matsumoto, Yiyang Dong, Kazuma Mawatari, Tadatomo Suga, Takehiko Kitamorii
Proceedings of Micro Total Analysis Systems , 2012, 1225-1227.[ PDF ]
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- Temperature-flexible cell microcontainers fabricated with a phosphorylcholine polymer hydrogel on chip
Yan Xu, Kazuma Mawatari, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori
Proceedings of Micro Total Analysis Systems , 2012, 1048-1050.[ PDF ]
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- Development of fluorine induced plasma activating room-temperature bonding strategy for high-pressure micro-nano fluidic devices
Kihoon Jang, Chenxi Wang, Yan Xu, Takehiko Kitamorii
Proceedings of Micro Total Analysis Systems , 2012, 1237-1239.[ PDF ]
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- Nano Laplace valve for femtolitter liquid generation and handling realized by nanopillar-in-nanochannel fabrication and surface modification
Kazuma Mawatari, Shogo Kubota, Yan Xu, Takehiko Kitamori
Proceedings of Micro Total Analysis Systems , 2012, 1447-1449.[ PDF ]
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2011
- Development of microfluidic platform for single-cell secretion analysis using a direct photoactive cell-attaching method
Kihoon Jang, Hong Trang Thi Ngo, Yo Tanaka, Yan Xu, Kazuma Mawatari, Takehiko Kitamori
Analytical Sciences , 2011, 27, 973-978. (doi:10.2116/analsci.27.973) [PDF]
( Featured on the cover of the journal; selected as a "Hot Article ")
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- Rapid screening of swine foot-and-mouth disease virus using micro-ELISA system
Yiyang Dong, Yan Xu, Zaixin Liu, Yuanfang Fu, Toshinor Ohashii, Yo Tanaka, Kazuma Mawatari, Takehiko Kitamori
Lab on a Chip , 2011, 11, 2153-2155. (DOI: 10.1039/C0LC00678E) [PDF]
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- Laplace pressure valve utilizing nano-in-nano structure toward attoliter scale liquid handling
Shogo Kubota, Kazuma Mawatari, Yan Xu, Takehiko Kitamori
Proceedings of Micro Total Analysis Systems, 2011, 1068-1070.[PDF]
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- 水による表面活性化を利用したガラスの低温接合
梅田準; 王晨曦; 許岩; 馬渡和真; 北森武彦; 須賀唯知
第25回エレクトロニクス実装学会講演大会論文集, 2011, 340-342.
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2010
- The biological performance of cell-containing phospholipid polymer hydrogels in bulk and microscale form
Yan Xu, Kihoon Jang, Tomohiro Konno, Kazuhiko Ishihara, Kazuma Mawatari, Takehiko Kitamori
Biomaterials, 2010, 31, 8839-8846.(doi:10.1016/j.biomaterials.2010.07.106) [PDF]
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- Single-cell attachment and culture method using a photochemical reaction in a closed microfluidic system
Kihoon Jang, Yan Xu, Yo Tanaka, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori
Biomicrofluidics, 2010, 4, 032208. (doi:10.1063/1.3494287) [PDF]
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- (Inside Cover) Cell-Compatible Hydrogel: A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions
Yan Xu, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kihoon Jang, Kazuhiko Ishihara, Takehiko Kitamori
Advanced Materials , 2010, 22. (DOI: 10.1002/adma.201090092) [PDF]
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- A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions
Yan Xu, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kihoon Jang, Kazuhiko Ishihara, Takehiko Kitamori
Advanced Materials , 2010, 22, 3017-3021. (DOI: 10.1002/adma.201000006) [PDF] [ESI]
( Selected as AA )
( Featured on the cover of the journal )
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- Phospholipid polymer biointerfaces for lab-on-a-chip devices
Yan Xu, Madoka Takai, Kazuhiko Ishihara
Annals of Biomedical Engineering, 2010, 38, 1938-1953. (DOI: 10.1007/s10439-010-0025-3) [PDF]
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- An efficient surface modification using 2-methacryloyloxyethyl phosphorylcholine to control cell attachment via photochemical reaction in a microchannel
Kihoon Jang, Kae Sato, Yo Tanaka, Yan Xu, Moritoshi Sato, Takahiro Nakajima, Kazuma Mawatari, Tomohiro Konno, Kazuhiko Ishihara,Takehiko Kitamori
Lab on a Chip, 2010, 10, 1937-1945. (DOI: 10.1039/C002239J) [PDF]
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- Cell-based toxin screening integrated with a cell-sustainable hydrogel on chip for onsite and portable applications
Yan Xu, Kihoon Jang, Kazuma Mawatari, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori
Proceedings of Micro Total Analysis Systems , 2010, 1, 1499-1501.[ PDF ]
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2009
- Protein adsorption and cell adhesion on cationic, neutral, and anionic 2-methacryloyloxyethyl phosphorylcholine copolymer surfaces
Yan Xu, Madoka Takai, Kazuhiko Ishihara
Biomaterials , 2009, 30, 4930-4938. (doi:10.1016/j.biomaterials.2009.06.005) [PDF]
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- Suppression of protein adsorption on a charged phospholipid polymer interface
Yan Xu, Madoka Takai, Kazuhiko Ishihara
Biomacromolecules , 2009, 10, 267-274. (DOI: 10.1021/bm801279y) [PDF]
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- An on-chip living cell bank
Yan Xu, Kae Sato, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori
Proceedings of Micro Total Analysis Systems , 2009, 2, 1952-1954.
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2008
- Long-term storage of living cells on chip for cell-based assays
Yan Xu, Kae Sato, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori
Proceedings of Micro Total Analysis Systems , 2008, 2, 1852-1854.[ PDF ]
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- リン脂質ポリマーを用いたマイクロ流体デバイスのバイオインターフェイス制御 (Functional Biointerface for Microfluidic Devices Using Phospholipid Polymers)
高井まどか, Yan Xu, James Sibarani, 石原一彦 (Modaka Takai, Yan Xu, James Sibarani, Kuzuhiko Ishihara)
高分子論文集 (KobunshiRonbunshu), 2008, 65, 3, 228-234. (doi:10.1295/koron.65.228) [PDF]
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2007
- (Cover) Microfluidic flow control on charged phospholipid polymer interface
Yan Xu, Madoka Takai, Tomohiro Konno, Kazuhiko Ishihara
Lab on a Chip , 2007, 7,149. (DOI: 10.1039/B700415J) [PDF]
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- Microfluidic flow control on charged phospholipid polymer interface
Yan Xu, Madoka Takai, Tomohiro Konno, Kazuhiko Ishihara
Lab on a Chip , 2007, 7,199-206. (DOI: 10.1039/B616851P) [PDF] [Correction]
( Featured on the cover of the journal, on Royal Society of Chemistry (RSC) web page, and on University of Tokyo-CNBI Topics, and was one of the ten most accessed articles of Lab on a chip in February, 2007)
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- Coating of anionic phospholipid polymer onto silica-based microchannel to minimize nonspecific protein adsorption
Yan Xu, Madoka Takai, Tomohiro Konno, Kazuhiko Ishihara
Key Engineering Materials , 2007, 342-343, 797-800. (doi:10.4028/www.scientific.net /KEM.342-343.797)
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- Charged phospholipid polymer surfaces with high cell adhesion resistance for cell chips
Yan Xu, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Proceedings of Micro Total Analysis Systems , 2007, 1, 424-426.
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2006
- Constructing biomembrane-mimic interface for cell separation in microfluidic chip
Yan Xu, Madoka Takai, Kazuhiko Ishihara
Transactions of Materials Research Society of Japan , 2006, 31, 645-648.
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- Protein antiadsorption modification by negatively charged phospholipid polymer for microsystem needing electroosmotic flow
Yan Xu, Madoka Takai, Tomohiro Konno, Kazuhiko Ishihara
Proceedings of Micro Total Analysis Systems, 2006, 1, 215-217.
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Before 2006
- Preparation of the soft tissue bulking agent composed of calcium alginate microspheres and its resorption in vivo
Yan Xu, We Wangi, Ying Xiong, Decai Bao, Xulang Zhang, Xiaojun Ma
Chinese Journal of Biomedical Engineering , 2004, 23, 448-454. (doi :10.3969/j.issn.0258-8021.2004.05.012)
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- The study on the PTC effect of CNT/CB PE composite filled
Mingyi Liao, Xue Li, Yan Xu, Yunfeng Li, Jieshan Qiu
China Synthetic Resin and Plastics , 2002, 19, 4-7.
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Patents
- Ma Xiaojun, Xu Yan, Wang Wei. Calcium alginate gel microsphere soft tissue reinforced material and its preparation method and application. China Patent, Patent Number(s): CN1628862-A, CN1306968-C.
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- Ma Xiaojun, Xu Yan, Wang Wei. Chitosan-calcium alginate gel microsphere soft tissue reinforced material and its preparation method and application. China Patent, Patent Number(s): CN1628861-A, CN1318100-C
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