Vision of the Research Center for BNCT (RC-BNCT)

Elemental Technologies Supporting BNCT and the OMU RC-BNCT

This center is engaged in the following research and social activities through industry-academia-government co-creation as a hub for R&D on boron agents that serve as the basis for greater innovations in BNCT and a wider scope of applications.

Research on Boron Agents

• Development of new boron agents
  Molecular design, exploratory synthesis, and biological evaluation of dodecaborate-containing molecular targeted boron agents with both tumor selectivity and advanced tumor accumulation
• R&D for Theranostics boron drug effective for both clinical and PET cancer diagnostics for BNCT
• Synthesis and evaluation of membrane-penetrating boronated peptides and antibodies that selectively accumulate in intracellular organelles
• DDS of boron drugs by extracellular vesicle exosomes

Research on FBPA, a Boron Probe for PET

• Development of new synthetic methods and equipment for ¹⁸FBPA using the F-minus method
• Pharmacokinetics of ¹⁸FBPA

Information Sharing and International Exchange

• Holding BNCT Nakamozu Seminars

Joint Research Promotion and Trainee Programs

• Promotion of joint research with universities inside and outside Japan, acceptance of trainees