Research Results
Jul 7, 2025
- Research Paper
- Posting / Publishing
- Paper / PressRelease
- Posting / Publishing
Paper by Prof. Yutaka Amao of Research Center for Artificial Photosynthesis et al. Selected for Cover of Catalysis Science & Technology
The paper titled "Heterogeneous catalytic hydrogenation of N-benzyl nicotinamide: a comparative study with nicotinamide adenine dinucleotide" by the research group led by Professor Yutaka Amao (Research Center for Artificial Photosynthesis) was published in Catalysis Science & Technology, a journal of the Royal Society of Chemistry (RSC), on May 7, 2025, and was featured on the cover of Issue 13 on July 7, 2025.
In this paper, it was discovered that N-benzyl nicotinamide (BNA+), a structural mimic of the coenzyme nicotinamide adenine dinucleotide (NAD+) required for various oxidoreductases, can be easily regenerated into 1,4-dihydro-N-benzyl nicotinamide (1,4-BNAH) simply by bubbling atmospheric hydrogen gas using a platinum-supported silica catalyst. While the regeneration of BNA+ into 1,4-BNAH is an essential process for effectively utilizing oxidoreductases, previous studies required light or electrical energy. The results of this research are expected to contribute to establishing a simple and efficient coenzyme regeneration process for useful substance production applications using oxidoreductases.
Comments from Professor Yutaka Amao
"The cover of this paper visualizes the regeneration of BNA+ into 1,4-BNAH on top of a platinum-supported silica catalyst, which is likened to a floating disc against a night sky backdrop."
Publication Information
| Journal: | Catalysis Science & Technology |
|---|---|
| Paper Title: | Heterogeneous catalytic hydrogenation of N-benzyl nicotinamide: a comparative study with nicotinamide adenine dinucleotide |
| Authors: | Makoto Hirano, Wataru Onodera, Masazumi Tamura, Yutaka Amao |
| Publication URL: | https://doi.org/10.1039/D5CY00202H |
Inquiries
Research Center for Artificial Photosynthesis, Osaka Metropolitan University
Professor Yutaka Amao
TEL: +81-6-6605-3726
E-mail：amao[at]omu.ac.jp
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