Research Results
Jul 7, 2025
- Research Paper
- Posting / Publishing
Paper by Prof. Yutaka Amao et al. of ReCAP Featured on the Cover of Catalysis Science & Technology, issued by the Royal Society of Chemistry (RSC)
A paper titled "Heterogeneous catalytic hydrogenation of N-benzyl nicotinamide: a comparative study with nicotinamide adenine dinucleotide," authored by Professor Yutaka Amao and his research group at the Research Center for Artificial Photosynthesis, was published in Catalysis Science & Technology, issued by the Royal Society of Chemistry (RSC), on May 7, 2025, and was featured on the cover of Issue 13 on July 7, 2025.
In this paper, the research group discovered that N-benzylnicotinamide (BNA+), a structural mimic of the coenzyme nicotinamide adenine dinucleotide (NAD+) required for various redox enzymes, can be easily regenerated into 1,4-dihydro-N-benzylnicotinamide (1,4-BNAH) simply by bubbling atmospheric hydrogen gas using a silica-supported platinum particle catalyst. While the regeneration of BNA+ into 1,4-BNAH is an essential process for the effective utilization of redox enzymes, previous studies required light or electrical energy. The results of this research are expected to contribute to the establishment of a simple and efficient coenzyme regeneration process for the application of useful substance production using redox enzymes.
Comment from Professor Yutaka Amao
The cover of this paper features the night sky as a backdrop, with the silica-supported platinum particle catalyst conceptualized as a floating disc. It illustrates the imagery of BNA+ being regenerated into 1,4-BNAH on this platform.
Publication Information
| Journal: | Catalysis Science & Technology |
|---|---|
| Paper Title: | Heterogeneous catalytic hydrogenation of N-benzyl nicotinamide: a comparative study with nicotinamide adenine dinucleotide |
| Authors: | Makoto Hirano, Wataru Onodera, Masazumi Tamura, Yutaka Amao |
| Publication URL: | https://doi.org/10.1039/D5CY00202H |
Contact Information
Research Center for Artificial Photosynthesis, Osaka Metropolitan University
Professor Yutaka Amao
TEL: +81-6-6605-3726
E-mail：amao[at]omu.ac.jp
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