English

Nutrition Chemistry Laboratory,
Department of Applied Biological Chemistry,
Graduate School of Agriculture,
Osaka Metropolitan University

 

Staffs

Professor

Ryoichi Yamaji, Ph.D.

yamaji#omu.ac.jp  

Associate Professor

Naoki Harada, Ph.D.

naoki.harada#omu.ac.jp  

Assistant Professor

Tomoya Kitakaze, Ph.D.

kitakaze#omu.ac.jp  



Please change# to @, when you send an e-mail.  


Publications

2022

1. Identification of G-protein coupled receptor 55 (GPR55) as a target of curcumin
Harada N, Okuyama M, Teraoka Y, Arahori Y, Shinmori Y, Horiuchi H, Luis P.B, Joseph A.I, Kitakaze T, Matsumura S, Hira T, Yamamoto N, Inui T, Goshima N, Schneider C, Inui H, and Yamaji R.
[npj Sci Food., in press]  

1. Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin.
Harada N, Okuyama M, Teraoka Y, Arahori Y, Shinmori Y, Horiuchi H, Luis P.B, Joseph A.I, Kitakaze T, Matsumura S, Hira T, Yamamoto N, Inui T, Goshima N, Schneider C, Inui H, and Yamaji R.
[NPJ Sci Food., 6, 4, 2022]

2. Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid.
Harada N, Arahori Y, Okuyama M, Luis P.B, Joseph A.I, Kitakaze T, Goshima N, Schneider C, Inui H, and Yamaji R.
[Biochem. Biophys. Res. Commun., 595, 41-46, 2022]

3. Carotenoid transporter CD36 expression depends on hypoxia-inducible factor-1α in mouse soleus muscles.
Kitakaze T, Sugihira T, Kameyama H, Maruchi A, Kobayashi Y, Harada N, and Yamaji R.
[J. Clin. Biochem. Nutr., in press]

2021

1. Oleamide rescues tibialis anterior muscle atrophy of mice housed in small cages
Kobayashi Y, Watanabe N, Kitakaze T, Izawa T, Sugimoto K, Kai K, Harada N, and Yamaji R.
[Br. J. Nutr., 126, 481-491, 2021]

2. Exopolysaccharides from a Scandinavian fermented milk viili increase butyric acid and Muribaculum members in the mouse gut
Yamane T, Handa S, Imai M, Harada N, Sakamoto T, Ishida T, Nakagaki T, Nakano Y.
[Food Chem. Mol. Sci., 3, 100042, 2021]

2020

1. Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice
Harada N, Hanada K, Minami Y, Kitakaze T, Ogata Y, Tokumoto H, Sato T, Kato S, Inui H, and Yamaji R.
[Am. J. Physiol. Endocrinol. Metab., 318, E525-E537, 2020]

2. Extracellular transglutaminase 2 induces myotube hypertrophy through G protein-coupled receptor 56
Kitakaze T, Yoshikawa M, Kobayashi Y, Kimura N, Goshima N, Ishikawa T, Ogata Y, Yamashita Y, Ashida H, Harada N, and Yamaji R.
[Biochim. Biophys. Acta - Mol. Cell Res., 1867, 118563, 2020]

3. β-Cryptoxanthin improves p62 accumulation and muscle atrophy in the soleus muscle of senescence-accelerated mouse-prone 1 mice
Noguchi M, Kitakaze T, Kobayashi Y, Mukai K, Harada N, and Yamaji R.
[Nutrients, 12, 2180, 2020]

4. Food texture affects glucose tolerance by altering pancreatic β-cell function in mice consuming high-fructose corn syrup
Harada N, Nomura M, Yoda Y, Matsumura S, Inui H, and Yamaji R.
[PLoS One, 15, e0233797, 2020]

5. Relationship between gut environment, feces-to-food ratio, and androgen deficiency-induced metabolic disorders
Harada N, Minami Y, Hanada K, Hanaoka R, Kobayashi Y, Izawa T, Sato T, Kato S, Inui H, and Yamaji R.
[Gut Microbes, 12, 1817719, 2020]

6. Biological activity of pseudovitamin B12 on cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase in mammalian cultured COS-7 cells
Bito T, Bito M, Hirooka T, Okamoto N, Harada N, Yamaji R, Nakano Y, Inui H, and Watanabe F.
[Molecules, 25, 3268, 2020]

7. Effects of crystalline and amorphous forms of paramylon from Euglena gracilis on the development of water-immersion restraint stress-induced gastric ulcer
Ogushi M, Imai M, Yoshizawa M, Suzuki K, and Harada N.
[Food Sci. Technol. Res., 26, 153-158, 2020]

8. Aronia juice supplementation inhibits lipid accumulation in both normal and obesity model mice
Yamane T, Imai M, Handa S, Harada N, Yamaji R, Sakamoto T, Ishida T, Inui H, Nakagaki T, Nakano Y.
[PharmaNutrition, 14, 100223, 2020]

9. Effects of caffeine and chlorogenic acid on nonalcoholic steatohepatitis in mice induced by choline-deficient, L-amino acid-defined, high-fat diet
Dungubat E, Watabe S, Togashi-Kumagai A, Watanabe M, Kobayashi Y, Harada N, Yamaji R, Fukusato T, Lodon G, Sevjid B, Takahashi Y.
[Nutrients, 12, 3886, 2020]

10. Effects of low ethanol consumption on nonalcoholic steatohepatitis in mice
Takahashi Y, Watabe S, Togashi-Kumagai A, Watanabe M, Dungubat E, Kusano H, Kobayashi Y, Harada N, Yamaji R, Sugimoto K, and Fukusato T.
[Alcohol, 87, 51-61, 2020]

11. Inhibitory effects of eucalyptus and banaba leaf extracts on nonalcoholic steatohepatitis induced by a high-fructose/high-glucose diet in rats
Takahashi Y, Sugimoto K, Soejima Y, Kumagai A, Koeda T, Shojo A, Nakagawa K, Harada N, Yamaji R, Inui H, Yamanouchi T, and Fukusato T.
[Prime Archives in Biomedical Sciences, 2020]

2019

1. Fetal androgen signaling defects affect pancreatic β-cell mass and function, leading to glucose intolerance in high-fat diet-fed male rats
Harada N, Yotsumoto Y, Katsuki T, Yoda Y, Masuda T, Nomura M, Shiraki N, Inui H, and Yamaji R.
[Am. J. Physiol. Endocrinol. Metab., 317, E731-E741, 2019]

2. 5-Hydroxy-7-methoxyflavone derivatives from Kaempferia parviflora induce skeletal muscle hypertrophy
Ono S, Yoshida N, Maekawa D, Kitakaze T, Kobayashi Y, Kitano T, Fujita T, Okuwa-Hayashi H, Harada N, Nakano Y, and Yamaji R.
[Food Sci. Nutr., 7, 312-321, 2019]

3. Tomatidine, a steroidal alkaloid from green tomatoes, reduces palmitate-induced lipid accumulation by activating AMPK via vitamin D receptor-mediated signaling in human HepG2 hepatocytes
Kusu H, Yoshida H, Kudo M, Okuyama M, Harada N, Tsuji-Naito K, and Akagawa M.
[Mol. Nutr. Food Res., 63, e1801377, 2019]

2018

1. Androgen signaling expands β-cell mass in male rats and β-cell androgen receptor is degraded under high-glucose conditions
Harada N, Yoda Y, Yotsumoto Y, Masuda T, Takahashi Y, Katsuki T, Kai K, Shiraki N, Inui H, and Yamaji R.
[Am. J. Physiol. Endocrinol. Metab., 314, E274-E286, 2018]

2. Stereoselective effects of lactate enantiomers on the enhancement of 3T3-L1 adipocyte differentiation
Harada N, Hirano I, Inui H, Yamaji R.
[Biochem. Biophys. Res. Commun., 498, 105-110, 2018]

3. Lactoferrin promotes murine C2C12 myoblast proliferation and differentiation, and myotube hypertrophy
Kitakaze T, Oshimo M, Kobayashi Y, Ryu M, Suzuki YA, Inui H, Harada N, and Yamaji R.
[Mol. Med. Rep., 17, 5912-5920, 2018]

4. Role of androgens in energy metabolism affecting on body composition, metabolic syndrome, type 2 diabetes, cardiovascular disease, and longevity: Lessons from a meta-analysis and rodent studies
Harada N.
[Biosci. Biotechnol. Biochem., 82, 1667-1682, 2018]

5. Theophylline suppresses interleukin-6 expression by inhibiting glucocorticoid receptor signaling in pre-adipocytes
Mitani T, Takaya T, Harada N, Katayama S, Yamaji R, Nakamura S, and Ashida H.
[Arch. Biochem. Biophys., 646, 98-106, 2018]

6. Heat stress prevents the decrease in succinate dehydrogenase activity in the extensor digitorum longus of streptozotocin-induced diabetic rats
Nonaka K, Une S, Komatsu R, Yamaji R, and Akiyama J.
[Physiol. Res., 67, 117-126, 2018]

2017

1. S-Equol activates cAMP signaling at the plasma membrane of INS-1 pancreatic β-cells and protects against streptozotocin-induced hyperglycemia by increasing β-cell function in male mice
Horiuchi H, Usami A, Shirai R, Harada N, Ikushiro S, Sakaki T, Nakano Y, Inui H, and Yamaji R.
[J. Nutr., 147, 1631-1639, 2017]

2. Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor β and increases skeletal muscle mass in young female mice
Ogawa M, Kitano T, Kawata N, Sugihira T, Kitakaze T, Harada N, and Yamaji R.
[J. Nutr. Biochem., 49, 63-70, 2017]

3. Lactoferrin induces tropoelastin expression by activating the lipoprotein receptor-related protein 1-mediated phosphatidylinositol 3-kinase/Akt pathway in human dermal fibroblasts
Ryu M, Nogami A, Kitakaze T, Harada N, Suzuki YA, and Yamaji R.
[Cell Biol. Int., 41, 1325-1334, 2017]

4. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) aggregation causes mitochondrial dysfunction during oxidative stress-induced cell death
Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T,  Azuma YT, Kuwamura M, Yamaji R, and Takeuchi T.
[J. Biol. Chem., 292, 4727-4742, 2017]

2016

1. Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice
Harada N, Hanaoka R, Horiuchi H, Kitakaze T, Mitani T, Inui H, and Yamaji R.
[Sci. Rep., 6, 23001, 2016]

2. pVHL-mediated degradation of HIF-2α regulates estrogen receptor α expression in normoxic breast cancer cells
Higashimura Y, Kitakaze T, Harada N, Inui H, Nakano Y, and Yamaji R.
[FEBS Lett., 590, 2690-2699, 2016]

3. The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy
Kitakaze T, Sakamoto T, Kitano T, Inoue N, Sugiura F, Harada N, and Yamaji R.
[Biochem. Biophys. Res. Commun., 478, 1292-1297, 2016]

4. Mogrol derived from Siraitia grosvenorii mogrosides suppresses 3T3-L1 adipocyte differentiation by reducing cAMP-response element-binding protein phosphorylation and increasing AMP-activated protein kinase phosphorylation
Harada N, Ishihara M, Horiuchi H, Ito Y, Tabata H, Suzuki YA, Nakano Y, Yamaji R, and Inui H.
[PLoS One, 11, e0162252, 2016]

5. Hypogonadism alters cecal and fecal microbiota in male mice
Harada N, Hanaoka R, Hanada K, Izawa T, Inui H, and Yamaji R.
[Gut Microbes, 7, 533-539, 2016]  

2015

1. Autophagic degradation of the androgen receptor mediated by increased phosphorylation of p62 suppresses apoptosis in hypoxia
Mitani T, Minami M, Harada N, Ashida H, and Yamaji R.
[Cell. Signal., 27, 1994-2001, 2015]

2. Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic β-cells
Harada N, Katsuki T, Takahashi Y, Masuda T, Yoshinaga M, Adachi T, Izawa T, Kuwamura M, Nakano Y, Yamaji R, and Inui H.
[J. Cell. Biochem., 116, 998-1006, 2015]

3. Female-specific regulation of skeletal muscle mass by USP19 in young mice
Ogawa M, Kitakaze T, Harada N, and Yamaji R.
[J. Endocrinol., 225, 135-145, 2015]

4. β-Carotene increases muscle mass and hypertrophy in the soleus muscle in mice
Kitakaze T, Harada N, Imagita H, and Yamaji R.
[J. Nutr. Sci. Vitaminol., 61, 481-487, 2015]

5. Protein arginine methyltransferase 10 is required for androgen-dependent proliferation of LNCaP prostate cancer cells
Harada N, Takagi T, Nakano Y, Yamaji R, and Inui H.
[Biosci. Biotechnol. Biochem., 79, 1430-1437, 2015]

6. Competitive and compensatory effects of androgen signaling and glucocorticoid signaling
Harada N, Inui H, and Yamaji R.
[Receptors Clin. Investig., 2, e785, 2015]

7. Inhibitory effects of Eucalyptus and Banaba leaf extracts on nonalcoholic steatohepatitis induced by a high-fructose/high-glucose diet in rats
Takahashi Y, Sugimoto K, Soejima Y, Kumagai A, Koeda T, Shojo A, Nakagawa K, Harada N, Yamaji R, Inui H, Yamanouchi T, and Fukusato T.
[Biomed. Res. Int., 2015, 296207, 2015]

8. Glyceraldehyde-3-phosphate dehydrogenase aggregates accelerate amyloid-β amyloidogenesis in Alzheimer disease
Itakura M, Nakajima H, Kubo T, Semi Y, Kume S, Higashida S, Kaneshige A, Kuwamura M, Harada N, Kita A, Azuma YT, Yamaji R, Inui T, and Takeuchi T.
[J. Biol. Chem., 290, 26072-26087, 2015]

9. Construction of sensitive reporter assay yeasts for comprehensive detection of ligand activities of human corticosteroid receptors through inactivation of CWP and PDR genes
Ito-Harashima S, Shiizaki K, Kawanishi M, Kakiuchi K, Onishi K, Yamaji R, and Yagi T.
[J. Pharmacol. Toxicol. Methods, 74, 41-52, 2015]

2014

1. Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells
Mitani T, Ito Y, Harada N, Nakano Y, Inui H, Ashida H, and Yamaji R.
[J. Nutr. Sci. Vitaminol., 60, 122-128, 2014]

2. Resveratrol inhibits hypoxia-inducible factor-1α-mediated androgen receptor signaling and represses tumor progression in castration-resistant prostate cancer
Mitani T, Harada N, Tanimori S, Nakano Y, Inui H, and Yamaji R.
[J. Nutr. Sci. Vitaminol., 60, 276-282, 2014]

3. S-Equol enantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells
Horiuchi H, Harada N, Adachi T, Nakano Y, Inui H, and Yamaji R.
[J. Nutr. Sci. Vitaminol., 60, 291-296, 2014]

4. Dodecylamine derivative of hydroxocobalamin acts as a potent inhibitor of cobalamin-dependent methionine synthase in mammalian cultured COS-7 cells
Bito T, Yasui M, Iwaki T, Yabuta Y, Ichiyanagi T, Yamaji R, Nakano Y, Inui H, and Watanabe F.
[Food Nutr. Sci., 5, 1311-1318, 2014]

2013

1. The preventive effect of β-carotene on denervation-induced soleus muscle atrophy in mice
Ogawa M, Kariya Y, Kitakaze T, Yamaji R, Harada N, Sakamoto T, Hosotani K, Nakano Y, and Inui H.
[Br. J. Nutr., 109, 1349-1358, 2013]

2. Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4´-amino-3,5-dihydroxy-trans-stilbene
Ito Y, Mitani T, Harada N, Isayama A, Tanimori S, Takenaka S, Nakano Y, Inui H, and Yamaji R.
[J. Nutr. Sci. Vitaminol., 59, 358-64, 2013]

3. Oligosaccharides from agar inhibit murine intestinal inflammation through the induction of heme oxygenase-1 expression
Higashimura Y, Naito Y, Takagi T, Mizushima K, Hirai Y, Harusato A, Ohnogi, H, Yamaji R, Inui H, Nakano Y, and Yoshikawa T.
[J. Gastroenterol., 48, 897-909, 2013]

4. Biochemical characterization of a GH53 endo-β-1,4-galactanase and GH35 exo-β-1,4-galactanase from Penicillium chrysogenum
Sakamoto T, Nishimura Y, Makino Y, Sunagawa Y, and Harada N.
[Appl. Microbiol. Biotechnol., 97, 2895-2906, 2013] 

2012

1. Coordinated action of hypoxia-inducible factor-1α and β-catenin in androgen receptor signaling
Mitani T, Harada N, Nakano Y, Inui H, and Yamaji R.
[J. Biol. Chem., 287, 33594-33606, 2012]

2. Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells
Harada N, Inoue K, Yamaji R, Nakano Y, and Inui H.
[Cancer Sci., 103, 1022-1027, 2012]

3. Glyceraldehyde-3-phosphate dehydrogenase regulates cyclooxygenase-2 expression by targeting mRNA stability
Ikeda I, Yamaji R, Irie K, Kioka N, and Murakami A.
[Arch. Biochem. Biophys., 528, 141-147, 2012]

2011

1. 17β-Estradiol represses myogenic differentiation by increasing ubiquitin-specific peptidase 19 through estrogen receptor α
Ogawa M, Yamaji R, Higashimura Y, Harada N, Ashida H, Nakano Y, and Inui H.
[J. Biol. Chem., 286, 41455-41465, 2011]

2. Hypoxia enhances transcriptional activity of androgen receptor through hypoxia-inducible factor-1α in a low androgen environment
Mitani T, Yamaji R, Higashimura Y, Harada N, Nakano Y, and Inui H.
[J. Steroid Biochem. Mol. Biol., 123, 58-64, 2011]

3. Inhibitory mechanisms of the transcriptional activity of androgen receptor by resveratrol: Implication of DNA binding and acetylation of the receptor
Harada N, Atarashi K, Murata Y, Yamaji R, Nakano Y, and Inui H.
[J. Steroid Biochem. Mol. Biol., 123, 65-70, 2011]

4. Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells
Higashimura Y, Nakajima Y, Yamaji R, Harada N, Shibasaki F, Nakano Y, and Inui H.
[Arch. Biochem. Biophys., 509, 1-8, 2011]

5. Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms
Higashimura Y, Terai T, Yamaji R, Mitani T, Ogawa M, Harada N, Inui H, and Nakano Y.
[Biochem. Biophys. Res. Commun., 413, 201-205, 2011]

6. Suppression of inducible nitric oxide synthase expression and amelioration of lipopolysaccharide-induced liver injury by polyphenolic compounds in Eucalyptus globulus leaf extract
Sugimoto K, Sakamoto S, Nakagawa K, Hayashi S, Harada N, Yamaji R, Nakano Y, and Inui H.
[Food Chem., 125, 442-446, 2011]

7. (-)-Epigallocatechin-3-gallate suppresses growth of AZ521 human gastric cancer cells by targeting the DEAD box RNA helicase p68
Tanaka T, Ishii T, Mizuno D, Mori T, Yamaji R, Nakamura Y, Kumazawa S, Nakayama T, and Akagawa M.
[Free Radic. Biol. Med., 50, 1324-1335, 2011]

8. Purification, characterization and gene cloning of two forms of a thermostable endo-xylanase from Streptomyces sp. SWU10
Deesukon W, Nishimura Y, Harada N, Sakamoto T, and Sukhumsirichart W.
[Process Biochem., 46, 2255-2262, 2011]

2010

1. Involvement of three glutamine tracts in human androgen receptor transactivation
Harada N, Mitani T, Higashimura Y, Yamaji R, Okamoto K, Nakano Y, and Inui H.
[J. Steroid Biochem. Mol. Biol., 118, 77-84, 2010]

2. Construction of a dominant negative form of human hypoxia-inducible factor-2α
Higashimura Y, Yamaji R, Harada N, Nakao M, Nakano Y, and Inui H.
[Biosci. Biotech. Biochem., 74, 2100-2102, 2010]

3. A yeast bioassay for androgenic and anti-androgenic compounds based on the NH2- and COOH-terminal interaction of androgen receptor
Ogawa M, Yamaji R, Mitani T, Murata Y, Nakao M, Harada N, Nakano Y, and Inui H.
[Biosci. Biotechnol. Biochem., 74, 1965-1968, 2010]

4. Eucalyptus leaf extract suppresses the postprandial elevation of portal, cardiac and peripheral fructose concentrations after sucrose ingestion in rats
Sugimoto K, Hosotani T, Kawasaki T, Nakagawa K, Hayashi S, Nakano Y, Inui H, and Yamanouchi T.
[J. Clin. Biochem. Nutr., 46, 205-211, 2010]

5. Digestion and absorption of Siraitia grosvenori triterpenoids in the rat
Murata Y, Ogawa T, Suzuki YA, Yoshikawa S, Inui H, Sugiura M, and Nakano Y.
[Biosci. Biotechnol. Biochem., 74, 673-676, 2010]

6. Methyladeninylcobamide functions as the cofactor of methionine synthase in a Cyanobacterium, Spirulina platensis NIES-39
Tanioka Y, Miyamoto E, Yabuta Y, Ohnishi K, Fujita T, Yamaji R, Misono H, Shigeoka S, Nakano Y, Inui H, and Watanabe F.
[FEBS Lett., 584, 3223-3226, 2010]

7. Sensitive and convenient yeast reporter assay for high-throughput analysis by using a secretory luciferase from Cypridina noctiluca
Tochigi Y, Sato N, Sahara T, Wu C, Saito S, Irie T. Fujibuchi W, Goda T, Yamaji R, Ogawa M, Ohmiya Y, and Ohgiya S.
[Anal. Chem., 82, 5768-5776, 2010]

8. Potential use of Bschofia javanica as an active ingredient of functional foods and cosmeceutical products possessing hyaluronidase, collagenase, tyrosinase and urease inhibitory effects
Barla F, Horinishi A, Harada N, Yamaji R, Enomoto T, Suzuki N, Maenaka H, Nakano Y, and Inui H.
[Jpn. J. Compl. Alternative Med., 7, 129-133, 2010]

2009

1. Cobalamin deficiency results in an abnormal increase in L-methylmalonyl-CoA mutase expression in rat liver and COS-7 cells
Nakao M, Hironaka S, Harada N, Adachi T, Bito T, Yabuta Y, Watanabe F, Miura T, Yamaji R, Inui H, and Nakano Y.
[Brit. J. Nutr., 101, 492-498, 2009]

2. Inhibitive effects of alkyl gallates on hyaluronidase and collagenase
Barla F, Higashijima H, Funai S, Sugimoto K, Harada N, Yamaji R, Fujita T, Nakano Y, and Inui H.
[Biosci. Biotechnol. Biochem., 73, 2335-2337, 2009]

3. Occurrence of pseudovitamin B12 and its possible function as the cofactor of cobalamin-dependent methionine synthase in a cyanobacterium Synechocystis sp. PCC680
Tanioka Y, Yabuta Y, Yamaji R, Shigeoka S, Nakano Y, Watanabe F, and Inui H.
[J. Nutr. Sci. Vitaminol., 55, 518-521, 2009]

4. Rats fed fructose-enriched diets have characteristics of nonalcoholic hepatic steatosis
Kawasaki T, Igarashi K, Koeda T, Sugimoto K, Nakagawa K, Hayashi S, Yamaji R, Inui H, Fukusato T, and Yamanouchi T.
[J. Nutr., 139, 2067-2071, 2009]

5. Hydrolyzable tannins as antioxidants in the leaf extract of Eucalyptus globulus possessing tyrosinase and hyaluronidase inhibitory activities
Sugimoto K, Nakagawa K, Hayashi S, Amakura Y, Yoshimura M, Yoshida T, Yamaji R, Nakano Y, and Inui H.
[Food Sci. Technol. Res., 15, 331-336, 2009]

2008

1. RanBP10 acts as a novel coactivator for the androgen receptor
Harada N, Yokoyama T, Yamaji R, Nakano Y, and Inui H.
[Biochem. Biophys. Res. Commun., 368, 121-125, 2008]

2. ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor
Harada N, Ohmori Y, Yamaji R, Higashimura Y, Okamoto K, Isohashi F, Nakano Y, and Inui H.
[Biochem. Biophys. Res. Commun., 373, 373-377, 2008]

3. Vitamin B12 deficiency results in abnormal regulation of serine dehydratase and tyrosine aminotransferase activities correlatad with impairment of the adenylyl cyclase system in rat liver
Ebara S, Nakao M, Tomoda M, Yamaji R, Watanabe F, Inui H, and Nakano Y.
[Brit. J. Nutr., 99, 503-510, 2008]

4. Analysis of vitamin B12 in food by silica gel 60 TLC and bioautography with vitamin B12-dependent Escherichia coli 215
Tanioka Y, Yabuta Y, Miyamoto E, Inui H, and Watanabe F.
[J. Liq. Chromatogr. Relat. Technol., 31, 1977-1985, 2008]

5. Covalent modification of proteins by green tea polyphenol (-)-epigallocatechin-3-gallate through autoxidation
Ishii T, Mori T, Tanaka T, Mizuno D, Yamaji R, Kumazuwa S, Nakayama T, and Akagawa M.
[Free Radic. Biol. Med., 45, 1384-1394, 2008]

2007

1. Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells
Harada N, Yasunaga R, Higashimura Y, Yamaji R, Fujimoto K, Moss J, Inui H, and Nakano Y.
[J. Biol. Chem., 282, 22651-22661, 2007]

2. Resveratol down-regulates the androgen receptor at the post-translational level in prostate cancer cells
Harada N, Murata Y, Yamaji R, Miura T, Inui H, and Nakano Y.
[J. Nutr. Sci. Vitaminol., 53, 556-560, 2007]

3. Antidiabetic effect of long-term supplementation with Siratia grosvenorion the spontaneously diabetic Goto-Kakizaki rat
Suzuki YA, Tomoda M, Murata Y, Inui H, Sugiura M, and Nakano Y.
[Brit. J. Nutr., 97, 770-775, 2007]

2006

1. Abnormal increase in the expression level of proliferation cell nuclear antigen (PCNA) in the liver and hepatic injury in rats with dietary cobalamin deficiency
Nakao M. Kono N. Adachi S. Ebara S. Adachi T. Miura. T. Yamaji R. Inui H, and Nakano Y.
[J. Nutr. Sci. Vitaminol., 52, 168-173, 2006]

2. Purification and characterization of a corrinoid-compound in an edible cyanobacterium Aphanizomenon flos-aquae as a nutritional supplementary food
Miyamoto E, Tanioka Y, Nakao M, Barla F, Inui H, Fujita T, Watanabe F, and Nakano Y.
[J. Agric. Food Chem., 54, 9604-9607, 2006]

3. Recent advances in molecular pharmacology of the histamine systems: organic cation transporters as a histamine transporter and histamine metabolism
Ogasawara M, Yamauchi K, Satoh YI, Yamaji R, Inui K, Jonker JW, Schinkel AH, and Maeyama K.
[J. Pharmacol. Sci., 101, 24-30, 2006]

4. Separation and properties of two novel NADP+-dependent alcohol dehydrogenases from Euglena gracilis Z
Munir I, Swati ZA, Rashid MH, Yamaji R, Inui H, and Nakano Y.
[Pak. J. Biol. Sci., 6, 2743-2747, 2006]

5. Subcellular localization of glyoxylate cycle key enzymes involved in oxalate biosynthesis of wood-destroying basidiomycete Fomitopsis palustris grown on glucose
Sakai S, Nishide T, Munir E, Baba K, Inui H, Nakano Y, Hattori T, and Shimada M.
[Microbiology, 152, 1857-1866, 2006]

6. Sweetness characteristics of the triterpene glycosides in Siraitia grosvenori
Murata Y, Yoshikawa S., Suzuki YA, Sugiura M, Inui H, and Nakano Y.
[Nippon Shokuhin Kagaku Kogaku Kaishi, 53, 527-533, 2006] 

2005

1. Glyceraldehyde-3-phosphate dehydrogenase in the extracellular space inhibits cell spreading
Yamaji R, Chatani E, Harada N, Sugimoto K, Inui H, and Nakano Y.
[Biochim. Biophys. Acta - Gen. Subjects, 1726, 261-271, 2005]

2. Eucalyptus leaf extract inhibits intestinal fructose absorption, and suppresses adiposity due to dietary sucrose in rats
Sugimoto K, Suzuki J, Nakagawa K, Hayashi S, Enomoto T, Fujita T, Yamaji R, Inui H, and Nakano Y.
[Brit. J. Nutr., 93, 957-963, 2005]

3. Triterpene glycosides of Siraitia grosvenori inhibit rat intestinal maltase and suppress the rise in blood glucose level after a single oral administration of maltose in rats
Suzuki YA, Murata Y, Inui H, Sugiura M, and Nakano Y.
[J. Agric. Food Chem., 53, 2941-2946, 2005]

4. Molecular characterization of a bifunctional glyoxylate cycle enzyme, malate synthase/isocitrate lyase, in Euglena gracilis
Nakazawa M, Minami T, Teramura K, Kumamoto S, Hanato S, Takenaka S, Ueda M, Inui H, Nakano Y, and Miyatake K.
[Comp. Biochem. Physiol. B, 141, 445-452, 2005]

2004

1. Hypoxic up-regulation of triosephosphate isomerase expression in mouse brain capillary endothelial cells
Yamaji R, Fujita K, Nakanishi I, Nagao K, Naito M, Tsuruo T, Inui H, and Nakano Y.
[Arch. Biochem. Biophys., 432, 332-342, 2004]

2. Characterization of corrinoid compounds from a Japanese black tea (Batabata-cha) fermented by bacteria
Kittaka-Katsura H, Ebara S, Watanabe F, and Nakano Y.
[J. Agric. Food Chem., 52, 909-911, 2004]

3. Purification and characterization of methylmalonyl-CoA mutase from a photosynthetic coccolithophorid alga, Pleurochrysis carterae
Miyamoto E, Watanabe F, Yamaguchi Y, Takenaka H, and Nakano Y.
[Comp. Biochem. Physiol. B, 138, 163-167, 2004]

4. Effect of carotenoids and ascorbic acid of Japanese persimmons on cellular lipid peroxidation in HepG2 cells
Hosotani K, Kawahata A, Koyama K, Murakami C, Yoshida H, Yamaji R, Inui H, and Nakano Y.
[Biofactors, 21, 241-245, 2004]

5. Induction and functional analysis of two reduced nicotinamide adenine dinucleotide phosphate-dependent glutathione peroxidase-like proteins in Synechocystis PCC 6803 during the progression of oxidative stress
Gaber A, Yoshimura K, Tamoi M, Takeda T, Nakano Y, and Shigeoka S.
[Plant Physiol., 136, 2855-2861, 2004]

6. Enzymatic high digestion of soybean milk residue (okara)
Kasai N, Murata A, Inui H, Sakamoto T, and Kahn RI.
[J. Agric. Food Chem., 52, 5709-5716, 2004]

2003

1. Hypoxia up-regulates glyceraldehyde-3-phosphate dehydrogenase in mouse brain capillary endothelial cells: involvement of Na+/Ca2+ exchanger
Yamaji R, Fujita K, Takahashi S, Yoneda H, Nagao K, Masuda W, Naito M, Tsuruo T, Miyatake K, Inui H, and Nakano Y.
[Biochim. Biophys. Acta - Mol. Cell Res., 1593, 269-276, 2003]

2. Hypoxia-induced megaloblastosis in vitamin B12-deficient rats
Ebara S, Adachi S, Takenaka S, Enomoto T, Watanabe F, Yamaji R, Inui H, and Nakano Y.
[Brit. J. Nutr., 89, 441-444, 2003]

3. Nitric oxide synthase induction, cGMP elevation, and biopterin synthesis in vascular smooth muscle cells stimulated with interleukin-1β in hypoxia
Nagao K, Takanaka S, Yamaji R, Inui H, and Nakano Y.
[J. Biochem., 133, 501-505, 2003]

4. Purification and characterization of homodimeric methylmalonyl-CoA mutase from Sinorhizobium meliloti
Miyamoto E, Watanabe F, Charles TC, Yamaji R, Inui H, and Nakano Y.
[Arch. Microbiol., 180, 151-154, 2003]

5. Presence of glyoxylate cycle enzymes in the mitochondria of Euglena gracilis
Ono K, Kondo M, Osafune T, Miyatake K, Inui H, Kitaoka S, Nishimura M, and Nakano Y.
[J. Eukaryot. Microbiol., 50, 92-96, 2003]

6. Translational regulation of histamine N-methyltransferase
Ogasawara M, Yamauchi K, Yamaji R, and Maeyama, K.
[J. Pharmacol. Sci., 91, 109P Suppl. 1]

7. Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes)
Inui M, Adachi T, Takenaka S, Inui H, Nakazawa M, Ueda M, Watanabe H, Mori C, Iguchi T, and Miyatake K.
[Toxicology, 194, 43-50, 2003]  

2002

1. Purification and characterization of a corrinoid compound from chlorella tablets as an algal health food
Kittaka-Katsura H, Fujita T, Watanabe F, and Nakano Y.
[J. Agric. Food Chem., 50, 4994-4997, 2002]

2. Uptake and physiological function of vitamin B12 in a photosynthetic unicellular coccolithophorid alga, Pleurochrysis carterae
Miyamoto Y, Watanabe F, Takenaka H, and Nakano Y.
[Biosci. Biotech. Biochem., 66, 195-198, 2002]

3. Occurrence of a novel NADP+-linked alcohol dehydrogenase in Euglena gracilis
Iqbal M, Nakazawa M, Harano K, Yamaji R, Inui H, Miyatake K, and Nakano Y.
[Comp. Biochem. Physiol., B132, 535-540, 2002]

4. Purification and characterization of Methylmalonyl-CoA mutase from a methanol-utilizing bacterium, Methylobacterium extorquens NR
Miyamoto E, Watanabe F, Yamaji R, Inui H, Sato K, and Nakano Y.
[J. Nutr. Sci. Vitaminol., 48, 242-246, 2002]

5. Effects of epigallocatechin 3-O-gallate on cellular antioxidative system in HepG2 cells
Murakami C, Hirakawa Y, Inui H, Nakano Y, and Yoshida H.
[J. Nutr. Sci. Vitaminol., 48, 89-94, 2002]

6. Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells.
Murakami C, Hirakawa Y, Inui H, Nakano Y, and Yoshida H.
[Biosci. Biotechnol. Biochem., 66, 1559-1562, 2002] 

2001

1. Inflammatory responses to lipopolysaccharide are suppressed in 40% energy-restricted mice
Matsuzaki J, Kuwamura M, Yamaji R, Inui H, and Nakano Y.
[J. Nutr., 131, 2139-2144, 2001]

2. Cobalamin deficiency results in severe metabolic disorder of serine and threonine in rats
Ebara S, Toyoshima T, Matsumura T, Adachi S, Takenaka S, Yamaji R, Watanabe F, Miyatake K, Inui H, and Nakano Y.
[Biochim. Biophys. Acta - Gen. Subjects, 1568, 111-117, 2001]

3. Characterization of a Vitamin B12 Compound from Unicellular Coccolithophorid Alga (Pleurochrysis carterae)
Miyamoto E, Watanabe F, Ebara S, Takenaka S, Takenaka H, Yamaguchi Y, Tanaka N, Inui H, and Nakano Y.
[J. Agric. Food Chem., 49, 3486-3489, 2001]

4. Inactive corrinoid-compound significantly decreases in spirulina platensis grown in a cobalt-deficient medium
Watanabe F, Miyamoto E, and Nakano Y.
[J. Agric. Food Chem., 49, 5685-5688, 2001]

5. Feeding dried purple laver (nori) to vitamin B12-deficient rats significantly improves vitamin B12 status
Takenaka S, Sugiyama S, Ebara S, Miyamoto E, Abe K, Tamura Y, Watanabe F, Tsuyama S, and Nakano Y.
[Brit. J. Nutr., 85, 699-703, 2001]

6. Characterization of a vitamin B12 compounds from edible shellfish, clam, oyster, and mussel
Watanabe F, Katsura H, Takenaka S, Enomoto T, Miyamoto E, Nakatsuka T, and Nakano Y.
[Int. J. Food Sci. Nutr., 52, 263-268, 2001]

7. Improvement of the flavor of canned satsuma mandarin with the essence
Takahashi H, Sumitani H, Inada Y, Mori D, and Nakano Y.
[Appl. Biol. Sci., 7, 49-56, 2001]

8. Characterization of monoclonal antibodies against ascorbate peroxidase isoenzymes: purification and epitope-mapping using immunoaffinity column chromatography
Yoshimura K, Ishikawa T, Wada K, Takeda T, Kamata Y, Tada T, Nishimura K, Nakano Y, and Shigeoka S.
[Biochim. Biophys. Acta - Gen. Subjects, 1526, 168-174, 2001]

9. NADPH-dependent glutathione peroxidase-like proteins (Gpx-1, Gpx-2) reduce unsaturated fatty acid hydroperoxides in Synechocystis PCC 6803
Gaber A, Tamoi M, Takeda T, Nakano Y, and Shigeoka S.
[FEBS Lett., 499, 32-36, 2001]

10. Expression of a gene encoding chitinase (pCA8ORF) from Aeromonas sp. No. 10S-24 in Escherichia coli enzyme characterization
Sutrisno A, Ueda M, Inui H, Kawaguchi T, Nakano Y, Arai M, and Miyatake K.
[J. Biosci. Bioeng., 91, 599-602, 2001]

11. Effect of barley on gastric juice secretion in rats with water immersion induced stress ulcer
Yoshizawa M, Nakano Y, and Nakamura H.
[J. Assoc. Dietary Fiber Res., 5, 21-27, 2001]


2000

1. Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex
Yamaji R, Adamik R, Takeda K, Togawa A, Pacheco-Rodriguez G, Ferrans VJ, Moss J, and Vaughan M.
[Proc. Natl. Acad. Sci. USA, 97, 2567-2572, 2000]

2. Implanted tumor growth is suppressed and survival is prolonged in sixty percent of food-restricted mice
Matsuzaki J, Yamaji R, Kiyomiya K, Kurebe M, Inui H, and Nakano Y.
[J. Nutr., 130, 111-115, 2000]

3. Increases in gastric histidine decarboxylase activity and plasma gastrin level in streptozotocin- induced type 1 diabetic rats
Inui H, Yasuno R, Takenoshita M, Ohnishi Y, Sakamoto M, Matsuzaki J, Yamaji R, Miyatake K, Yamatodani A, and Nakano Y.
[J. Nutr. Sci. Vitaminol., 46, 144-148, 2000]

4. Characterization of a vitamin B12 compound in the edible purple laver, Porphyra yezoensis
Watanabe F, Takenaka S, Katsura H, Miyamoto E, Abe K, Tamura Y, Nakatsuka T, and Nakano Y.
[Biosci. Biotech. Biochem., 64, 2712-2715, 2000]

5. The improvement of the flavor of canned satsuma mandarin
Takahashi H, Sumitani H, Inada Y, Mori D, and Nakano Y.
[Appl. Biol. Sci., 6, 67-73, 2000]

6. Effect of light-induced riboflavin degradation on the loss of cobalamin in milk
Watanabe F, Katsura H, Abe K, and Nakano Y.
[J. Home Econ. Jpn., 51, 231-234, 2000]

7. The origin of pyruvate:NADP+ oxidoreductase in mitochondria of Euglena gracilis
Nakazawa M, Inui H, Yamaji R, Yamamoto T, Takenaka S, Ueda M, Nakano Y, and Miyatake K.
[FEBS Lett., 479, 155-157, 2000]

1999

1. Disordered expression of the sucrase-isomaltase complex in the small intestine in Otsuka Long-Evans Tokushima fatty rats, a model of non-insulin-dependent diabetes mellitus with insulin resistance
Adachi T, Takenoshita M, Katsura H, Yasuda K, Tsuda K, Seino Y, Enomoto T, Yamaji R, Miyatake K, Inui H, and Nakano Y.
[Biochim. Biophys. Acta - Gen. Subjects, 1426, 126-132, 1999]

2. Purification and characterization of ADP-ribosyl cyclase from Euglena gracilis
Masuda W, Takenaka S, Tsuyama S, Inui H, Miyatake K, and Nakano Y.
[J. Biochem., 125, 449-453, 1999]

3. Dried green and purple lavers (Nori) contain substantial amounts of biologically active vitamin B12 but less of dietary iodine relative to other edible seaweeds
Watanabe F, Takenaka S, Katsura H, Mazumder ZH, Abe K, Tamura Y, and Nakano Y.
[J. Agric. Food Chem., 47, 2341-2343, 1999]

4. Pseudovitamin B12 is the predominant cobamide of an algal health food, spirulina tablets
Watanabe F, Katsura H, Takenaka S, Fujita T, Abe K, Tamura T, Nakatsuka T, and Nakano Y.
[J. Agric. Food Chem., 47, 4736-4741, 1999]


1998

1. Suppressive effect of insulin on the synthesis of sucrase-isomaltase complex in small intestinal epithelial cells, and abnormal increase in the complex under diabetic conditions
Takenoshita M, Yamaji R, Inui H, Miyatake K, and Nakano Y.
[Biochem. J., 329, 597-600, 1998]

2. The intron 5-inserted form of rat erythropoietin receptor is expressed as a membrane-bound form
Yamaji R, Murakami C, Takenoshita M, Tsuyama S, Inui H, Miyatake K, and Nakano Y.
[Biochim. Biophys. Acta - Mol. Cell Res., 1403, 169-178, 1998]

3. Effect of microwave heating on the loss of vitamin B12 in foods
Watanabe F, Abe K, Fujita T, Goto M, Hiemoti M, and Nakano Y.
[J. Agric. Food Chem., 46, 206-210, 1998]

4. Comparison of microbiological assay and a fully automated chemiluminescent system for the determination of vitamin B12 in food
Watanabe F, Takenaka S, Abe K, Tamura Y, and Nakano Y.
[J. Agric. Food Chem., 46, 1433-1436, 1998]

5. Biological activity of hydroxo-vitamin B12 degradation product formed during microwave heating
Watanabe F, Abe K, Katsura H, Takenaka S, Mazumder ZH, Yamaji R, Ebara S, Fujita T, Tanimori S, Kirihata M, and Nakano Y.
[J. Agric. Food Chem., 46, 5177-5180, 1998]

6. α2-Adrenoceptor-mediated antisecretory effect of hypoxia in conscious rats
Yamaji R, Ohnishi Y, Sakamoto M, Takenoshita M, Ohta M, Tsuyama S, Watanabe F, Inui H, Miyatake K, and Nakano Y.
[Biosci. Biotech. Biochem., 62, 546-549, 1998]

7. Low sucrase activity in the small intestine of a senescence-accelerated strain of mouse, SAMP1
Takenoshita M, Yabune M, Katsura H, Yamaji R, Inui H, Miyatake K, and Nakano Y.
[Biosci. Biotech. Biochem., 62, 965-969, 1998]

8. Suppression by water extracts of sophora plants of sucrose-induced hyperglycemia in rats and inhibition of intestinal disaccharidases in vitro
Shi H, Huang Q, Yamaji R, Inui H, Fujita T, Miyatake K, Nakano Y, Tada T, and Nishimura K.
[Biosci. Biotech. Biochem., 62, 1225-1227, 1998]

9. Occurrence of vitamin B12 coenzymes in an halotolerant green alga, Dunaliella tertiolecta
Watanabe F, Abe K, Katsura H, Takenaka S, Mazumder ZH, Tamura Y, and Nakano Y.
[Appl. Biol. Sci., 4, 17-26, 1998]

10. Propionic acid metabolism in Euglena gracilis Z I. effect of ammonium ion
Mazumder ZH, Inui H, Ueda M, Miyatake K, Haranou K, and Nakano Y.
[Appl. Biol. Sci., 4, 37-46, 1998]

11. Inhibition of aldose reductases by α-and β-glucosides from A Perilla and possible implications for recognition of α-and β-glucoside configuration
Fujita T, Ohira K, Takenoshita M, Nakatsuka T, Yamaji R, Ueda M, Miyatake K, Nakayama M, and Nakano Y.
[Appl. Biol. Sci., 4, 123-134, 1998]

12. Effects of CO2 and O2 concentrations and light intensity on growth of microalgae (Euglena gracilis) in CELSS
Kitaya Y, Kibe S, Oguchi M, Tanaka H, Miyatake K, and Nakano Y.
[Life Support Biosph. Sci., 5, 243-247, 1998]

1997

1. Oscillation of ADP-ribosyl cyclase activity during the cell cycle and function of cyclic ADP-ribose in a unicellular organism, Euglena gracilis
Masuda W, Takenaka S, Inageda K, Nishina H, Takahashi K, Katada T, Tsuyama S, Inui H, Miyatake K, and Nakano Y.
[FEBS Lett., 405, 104-106, 1997]

2. Method for quantitation of total vitamin B12 in foods using a highly fluorescent vitamin B12 derivative
Watanabe F, Abe K, Takenaka S, Fujita T, and Nakano Y.
[J. Agric. Food Chem., 45, 4661-4663, 1997]

3. Inositol 1,4,5-trisphosphate and dyclic ADP-ribose mobilize Ca2+ in a protist, Euglena gracilis
Masuda W, Takenaka S, Tsuyama S, Tokunaga M, Yamaji R, Inui H, Miyatake K, and Nakano Y.
[Comp. Biochem. Physiol., 118C, 279-283, 1997]

4. Accumulation of trehalose as a compatible solute under osmotic stress in Euglena gracilis Z
Takenaka S, Kondo T, Nazeri S, Tamura Y, Tokunaga M, Tsuyama S, Miyatake K, and Nakano Y.
[J. Euk. Microbiol., 44, 609-613, 1997]

5. Effect of carnosine and anserine on the destruction of vitamin B12 with vitamin C in the presence of copper
Takenaka S, Sugiyama S, Watanabe F, Abe K, Tamura Y, and Nakano Y.
[Biosci. Biotech. Biochem., 61, 2137-2139, 1997]

6. Occurrence of Cobalamin Coenzymes in the Photosynthetic Green Alga
Watanabe F, Abe K, Takenaka S, Tamura Y, Maruyama I, and Nakano Y.
[Biosci. Biotech. Biochem., 61, 896-897, 1997]

7. Salt-torerant Mechanism of a Protozoan, Eugelana gracilis Z
Nakano Y, Miyatake K, Watanabe F, and Takenaka S.
[Salt Sci. Res. Foundation Ann. Res. Rep., 367-376, 1997]

8. Growth of Euglena, a photosynthetic alga, by light emitting diodes
Aiga I, Kiyota M, Matsumoto T, Yamaji R, Nakano Y, Miyatake K, Takenaka S, Masuda W, Jinda T, Horaguchi K, Wasa K, and Kondo J.
[CELSS J., 9, 7-12, 1997]

1996

1. Brain capillary endothelial cells express two forms of erythropoietinreceptor mRNA
Yamaji R, Okada T, Naito M, Tsuruo T, Miyatake K, and Nakano Y.
[Eur. J. Biochem., 239, 494-500, 1996]

2. Hypoxia inhibits gastric emptying and gastric acid secretion in conscious rats
Yamaji R, Sakamoto M, Miyatake K, Nakano Y.
[J. Nutr., 126, 673-680, 1996]

3. Mitochondrial NADH-linked aquacobalamin reductase activity is low in human skin fibroblasts with defects in synthesis of cobalamin coenzymes
Watanabe F, Saido H, Yamaji R, Miyatake K, Isegawa Y, Ito A, Yubisui T, Rosenblatt DS, and Nakano Y.
[J. Nutr., 126, 2947-2951, 1996]

4. Effect of cobalamin deficiency on the biosynthesis of phosphatidylcholine in Euglena gracilis
Inui H, Ohya O, Isegawa Y, Kitaoka S, Miyatake K, and Nakano Y.
[J. Euk. Microbiol., 43, 177-180, 1996]

5. Accumulation of methylmalonic acid caused by vitamin B12-deficiency disrupts normal cellular metabolism in rat liver
Toyoshima S, Watanabe F, Saido H, Pezacka E, Jakobsen D, Miyatake K, and Nakano Y.
[Brit. J. Nutr., 75, 929-938, 1996]

6. Purification and characterization of arginine: mono-ADP-ribosylhydrolase from Euglena gracilis Z
Takenaka S, Masuda W, Tsuyama S, Tamura Y, Miyatake K, and Nakano Y.
[J. Biochem., 120, 792-796, 1996]

7. Adenosylcobalamin-dependent methylmalonyl-CoA mutase isozymes in the phtosynthetic protozoon Euglena gracilis Z
Watanabe F, Abe K, Tamura Y, and Nakano Y.
[Microbiology, 142, 2631-2634, 1996]

8. Characterization of niacin of skipjack tuna muscle and change of the niacin content during storage
Watanabe F, Goto M, Abe K, Nakano Y.
[J. Jpn. Soc. Cold Preserva. Food, 22, 165-168, 1996]

9. Glutathione peroxidase activity during storage of fish muscle
Watanabe F, Goto M, Abe K, and Nakano Y.
[J. Food Sci., 61, 734-735, 1996]

10. Euglena gracilis fermentative wax ester production
Abe K, Watanabe F, Masuda W, Inui H, Miyatake K, and Nakano Y.
[Appl. Biol. Sci., 2, 33-40, 1996]

11. Different location in dark-adapted leaves of phaseolus vulgaris of ribulose-1,5-bisphosphatecarboxylase/oxygenase and 2-carboxyarabinitol 1-phosphate
Anwaruzzaman, Nakano Y, and Yokota A.
[FEBS Lett., 388, 223-227, 1996]

12. Purification and characterization of serine hydroxymethyltransferase from mitochondria of Euglena gracilis Z
Sakamoto M, Masuda T, Yanagimoto Y, Nakano Y, Kitaoka S, and Tanigawa Y.
[Biosci. Biotech. Biochem., 60, 1941-1944, 1996]

13. Growth of photosynthetic algae Euglena in high CO2 conditions and its photosynthetic characteristics
Nakano Y, Miyatake K, Okuno H, Hamazaki K, Takenaka S, Honami N, Kiyota M, Aiga I, and Kondo J.
[Acta Hort.,440, 49-54, 1996]

14. K project: production of food by biological fixation of CO2
Kondo J, Aiga I, Nakano Y, and Miyatake K.
[Acta Hort., 440, 645-650, 1996]