業績

主な研究業績

2023

  • Yasugi M*, Nakagama Y, Kaku N, Nitahara Y, Hatanaka N, Yamasaki S, Kido Y. Characteristics of epitope dominance pattern and cross-variant neutralization in 16 SARS-CoV-2 mRNA vaccine sera. Vaccine. 41:6248-54, 2023.
  • Katahira J, Ohmae T, Yasugi M, Sasaki R, Itoh Y, Kohda T, Hieda M, Yokota-Hirai M, Okamoto T, Miyamoto Y. Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex. Nucleic Acids Res. 51:7602-18, 2023.
  • Teshima K, Tanaka T, Ye Z, Ikeda K, Matsuzaki T, Shiroma T, Muroya A, Hosoda M, Yasugi M, Komatsu H. Antiviral activity of curcumin and its analogs selected by an artificial intelligence-supported activity prediction system in SARS-CoV-2-infected VeroE6  cells. Nat Prod Res. 2023. doi: 10.1080/14786419.2023.2194647.
  • Yasugi M*, Hatoya S, Motooka D, Kondo D, Akiyoshi H, Horie M, Nakamura S, Shimada T. Genetic and phenotypic analyses of mcr-harboring extended-spectrum beta-lactamase-producing Escherichia coli isolates from companion dogs and cats in Japan. Vet Microbiol. 280:109695, 2023.
  • Nakagama Y, Candray K, Kaku N, Komase Y, Rodriguez-Funes MV, Dominguez R, Tsuchida T, Kunishima H, Nagai E, Adachi E, Ngoyi DM, Yamasue M, Komiya K, Hiramatsu K, Uemura N, Sugiura Y, Yasugi M, Yamagishi Y, Mikamo H, Shiraishi S, Izumo T, Nakagama S, Watanabe C, Nitahara Y, Tshibangu-Kabamba E, Kakeya H, Kido Y. Antibody avidity maturation following recovery from infection or the booster vaccination grants beadth of SARS-CoV-2 neutralizing capacity. J Infect Dis. 227(6):780-787, 2023.                

                                                                                

2022

  • Yasugi M*, Komura Y, Ishigami Y. Mechanisms underlying inactivation of SARS-CoV-2 by nano-sized electrostatic atomized water particles. J Nanopart Res. 24:1-14, 2022.
  • Hatanaka N, Awasthi SP, Xu B, Goda H, Kawata H, Horiuchi I, Yasugi M, Yamasaki S*. Comparative evaluation of chlorous acid and sodium hypochlorite activity against SARS-CoV-2. Access Microbiol. 4:000354, 2022.
  • Komatsu H*, Tanaka T, Ye Z, Ikeda K, Matsuzaki T, Yasugi M, Hosoda M. Identification of SARS-CoV-2 main protease inhibitors from FDA-approved drugs by artificial intelligence-supported activity prediction system. J Biomol Struct Dyn. 5:1-9, 2022.
  • Wakabayashi Y, Takemoto K, Iwasaki S, Yajima T, Kido A, Yamauchi A, Kuroiwa K, Kumai Y, Yoshihara S, Tokumoto H, Kawatsu K, Yasugi M, Miyake M*. Isolation and characterization of Staphylococcus argenteus strains from retail foods and slaughterhouses in Japan. Int J Food Microbiol. 363:109503, 2022.
  • Hatanaka N, Xu B, Yamashita Y, Kawakami H, Yasugi M, Yamasaki S*. Shellcoat, a calcinated calcium solution, effectively inactivates SARS-CoV-2. Bio Sci. 27:53-56, 2022.
  • Ishimoto K, Hatanaka N, Otani S, Maeda S, Xu B, Yasugi M, Moore JE, Suzuki M, Nakagawa S, Yamasaki S*. Tea crude extracts effectively inactivate severe acute respiratory syndrome coronavirus 2. Lett Appl Microbiol. 74:2-7, 2022.

2021

  • Takakuwa T, Nakagama Y, Yasugi M, Maeda T, Matsuo K, Kiritoshi A, Deguchi R, Hagawa N, Shibata W, Oshima K, Yamamoto K, Uchida K, Noda T, Yamada K, Nishimura T, Yamamoto H, Kido Y*, Hino M, Kakeya H, Mizobata Y. Discrepant antigen-specific antibody responses causing SARS-CoV-2 persistance in a patient receiving B-cell-targeted therapy with rituximab. Intern Med. 60:3827-31, 2021.
  • Nitahara Y, Nakagama Y, Kaku N, Candray K, Michimuko Y, Tshibangu-Kabamba E, Kaneko A, Yamamoto H, Mizobata Y, Kakeya H, Yasugi M, Kido Y*. High-resolution linear epitope mapping of the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 mRNA vaccine recipients. Microbiol Spectr. 9:e0096521, 2021.
  • Hatanaka N, Xu B, Yasugi M, Morino H, Tagishi H, Miura T, Shibata T, Yamasaki S*. Chlorine dioxide is a more potentantiviral agent against SARS-CoV-2 than sodium hypochlorite. J Hosp Infect. 118:20-26, 2021.
  • Hatanaka N, Yasugi M, Sato T, Mukamoto M, Yamasaki S*. Hypochlorous acid solution is a potent antiviral agent against SARS-CoV-2. J Appl Microbiol. 132:1496-1502, 2021.
  • 國武広一郎*,村上拡,佃一訓,小崎俊司,安木真世. 低濃度エタノールと界面活性剤の併用による新型コロナウイルスに対する不活化効果. 日本食品微生物学会雑誌. 38:93-97, 2021.
  • 安木真世*,黒田真未,井千尋. 低濃度の有機物存在下におけるオゾン水の新型コロナウイルスに対する不活化効果. 室内環境学会誌. 24:13-18, 2021.
  • Yasugi M*, Hatoya S, Motooka D, Matsumoto Y, Shimamura S, Tani H, Furuya M, Mie K, Miyake M, Nakamura S, Shimada T. Whole-genome analyses of extended-spectrum or AmpC beta-lactamase-producing Escherichia coli isolates from companion dogs in Japan. Plos One. 16:e0246482, 2021.

2020

  • 安木真世*,小村泰浩,石上陽平. 帯電微粒子水の新型コロナウイルスに対する不活化効果. 室内環境学会誌. 23:241-246, 2020.
  • Yasugi M*, Motooka D, Nakamura S, Miyake M. Phosphorothioation of foreign DNA influences the transformation efficiency in Clostridium perfringens NCTC8239, Anaerobe. 61:1-9, 2020.

2019

  • Kanegi R, Yasugi M, Nabetani T, Tanaka T, Wada Y, Hirai K, Sugiura K, Hatoya S*. Clinical findings and treatment of disseminated ‘Mycobacterium avium subspecies hominissuis’ hominissuis infection in a domestic cat. J Vet Med Sci. 81:1842-1849, 2019.

  • Wakabayashi Y, Nariya H, Yasugi M, Kuwahara T, Sarker MR, Miyake M*. An enhanced green fluorescence protein (EGFP)-based reporter assay for quantitative detection of sporulation in Clostridium perfringens SM101. Int J Food Microbiol. 291:144-50, 2019.

2018

  • Sakanoue H, Yasugi M, Miyake M*. Effect of sublethal heat treatment on the later stage of germination-to-outgrowth of Clostridium perfringens spores. Microbiol Immunol. 62:418-24, 2018.
  • Sakanoue H, Nakano T, Sano K, Yasugi M, Monma C, Miyake M*. Adherence of Clostridium perfringens spores to human intestinal epithelial Caco-2 cells. FEMS Microbiol Lett. 365, 2018.
  • Inoue H, Suzuki T, Hyodo M, Miyake M. Evaluation of multinomial logistic regression models for predicting causative pathogens of food poisoning cases. J Vet Med Sci. 80:1223-1227, 2018.
  • Miyake M*, Kohda T, Yasugi M, Sakanoue H, Hirata S, Spores of anaerobic bacteria; characteristics and their behaviors during restoration from damaged status. 日本食品科学工学会誌. 65:142-7, 2018.

2016

  • Yasugi M*, Otsuka K, Miyake M. Nitrate salts suppress sporulation and production of enterotoxin in Clostridium perfringens strain NCTC8239. Microbiol Immunol. 60:657-68, 2016.
  • Misaki R, Fukura N, Kajiura H, Yasugi M, Kubota-Koketsu R, Sasaki T, Momota M, Ono K, Ohashi T, Ikuta K, Fujiyama K*. Recombinant production and characterization of human anti-influenza virus monoclonal antibodies identified from hybridomas fused with human lymphocytes. Biologicals. 44:394-402, 2016.
  • Yasugi M*, Okuzaki D, Kuwana R, Takamatsu H, Fujita M, Sarker MR, Miyake M. Transcriptional profile during deoxycholate-induced sporulation in a Clostridium perfringens isolate causing foodborne illness. Appl Environ Microbiol. 82:2929-42, 2016.

2015

  • Yasugi M*, Sugahara Y, Hoshi H, Kondo K, Talukdar PK, Sarker MR, Yamamoto S, Kamata Y, Miyake M. In vitro cytotoxicity induced by Clostridium perfringens isolate carrying a chromosomal cpe gene is exclusively dependent on sporulation and enterotoxin production. Microbial Pathog. 85:1-10, 2015.
  • Nakamura S, Horie M, Daidoji T, Honda T, Yasugi M, Kuno A, Komori T, Okuzaki D, Narimatsu H, Nakaya T, Tomonoga T*. Influenza A virus-induced expression of a GalNAc transferase, GALNT3, via microRNAs is required for enhanced viral replicaion. J Virol. 90:1788-1801, 2015.
  • Daidoji T, Watanabe Y, Ibrahim MS, Yasugi M, Maruyama H, Masuda T, Arai F, Ohba T, Honda A, Ikuta K, Nakaya T*. Avian influenza virus infection of immortalized human respiratory epithelial cells depends upon a delicate balance between hemagglutinin acid stability and endosomal pH. J Biol Chem. 290:10627-42, 2015.
  • Le DQ, Morishita A, Tokonami S, Nishino T, Shiigi H, Miyake M, Nagaoka T. Voltammetric detection and profiling of isoprenoid quinones hydrophobically transferred from bacterial cells. Anal Chem. 87: 8416-23, 2015.

2014年以前については随時追加予定