業績一覧

The usefulness of full-thickness biopsy during semi-rigid pleuroscopy for differentiating between malignant pleural mesothelioma and non-specific pleurisy
Ueda T, Nakai T, Tanaka S, Nagamine H, Miyamoto A, Nishimura M, Matsumoto Y, Sato K, Yamada K, Watanabe T, Asai K, Matsumoto Y, Mikami Y, Kawaguchi T
BMC Pulm Med. 2025 Dec 10;25(1):553. doi: 10.1186/s12890-025-03982-6.PMID: 41366665
Association between pleurodesis before immunotherapy and pneumonitis in non-small cell lung cancer
Mizutani M, Ihara Y, Sawa K, Sugimoto A, Nagamine H, Matsumoto Y, Tani Y, Oka Y, Kaneda H, Bito T, Kawaguchi T, Shintani A
Respir Investig. 2025 Nov;63(6):1194-1200. doi: 10.1016/j.resinv.2025.09.016. Epub 2025 Sep 25.PMID: 41004952
Real-World Safety and Effectiveness of Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Asthma: Final Analysis of a Post-Marketing Surveillance in Japan
Asai K, Morioka Y, Ito R, Komatsubara M, Maruoka H
Adv Ther. 2026 Jan;43(1):317-332. doi: 10.1007/s12325-025-03421-2. Epub 2025 Nov 28.PMID: 41313548
Prevalence of dysfunctional breathing in the Japanese community and the involvement of tobacco use status: The JASTIS study 2024
Hirai K, Yamada K, Asai K, Tsutsumi M, Ueda T, Toyokura E, Furukawa Y, Miyamoto A, Nishimura M, Sato K, Watanabe T, Maruoka S, Gon Y, Tabuchi T, Kawaguchi T.
Respir Investig. 2025 Nov;63(6):1377-1382. doi: 10.1016/j.resinv.2025.10.002. Epub 2025 Nov 12.PMID: 41260862
Dual use of combustible and heated tobacco products associates persistent symptoms with a history of COVID-19: a JASTIS 2023 cross‑sectional study
Toyokura E, Yamada K, Asai K, Tsutsumi M, Ueda T, Hirai K, Furukawa Y, Miyamoto A, Nishimura M, Sato K, Watanabe T, Tabuchi T, Kawaguchi T
Sci Rep. 2025 Nov 14;15(1):38659. doi: 10.1038/s41598-025-22050-x.PMID: 41238605
Differences in Lung Cancer-related Clinical Practice and Basic Research Background between Japan and China: A Narrative Review
Wang L, Miao Y, Gu Y, Kawaguchi T, Mizutani M, Nakai T, Watanabe T, Asai K, Zhang H, Cai W, Tani Y, Kaneda H
Intern Med. 2025 Sep 1;64(17):2524-2533. doi: 10.2169/internalmedicine.4808-24. Epub 2025 Mar 1.PMID: 40024741
Impact of physical activity on respiratory disease: Current status and therapeutic implications
Asai K
Respir Investig. 2025 Nov;63(6):1187-1193. doi: 10.1016/j.resinv.2025.09.020. Epub 2025 Sep 25.PMID: 41004951
Application of endobronchial ultrasound-guided cryobiopsy for centrally located intrapulmonary lesions: A retrospective cohort study
Nakai T, Tanaka S, Nagamine H, Miyamoto A, Nishimura M, Matsumoto Y, Sato K, Yamada K, Watanabe T, Asai K, Matsumoto Y, Mikami Y, Kawaguchi T
Lung Cancer. 2025 Jul:205:108636. doi: 10.1016/j.lungcan.2025.108636. Epub 2025 Jun 24.PMID: 40570408
Relationship Between T790M Allele Frequency and Therapeutic Effects Before and After EGFR-TKI Administration Using Droplet Digital PCR in Non-small-cell Lung Cancer With EGFR Mutation
Ogawa K, Kaneda H, Koh Y, Matsumoto Y, Sawa K, Tamiya M, Ishikawa N, Minami K, Suzuki H, Eguchi Y, Kanazu M, Sato Y, Kawaguchi T.
Cancer Diagn Progn. 2025 May 3;5(3):285-299. doi: 10.21873/cdp.10441. eCollection 2025 May-Jun.PMID: 40322218
Long-term, real-world effectiveness of biologics for severe uncontrolled asthma: The PROSPECT study
Asai K, Iwanaga T, Takahashi M, Eda M, Hirai T, Yabuta T, Makita N, Tohda Y
Respir Investig. 2025 May;63(3):444-452. doi: 10.1016/j.resinv.2025.03.007. Epub 2025 Apr 4.PMID: 40186961
Respiratory Muscle Strength as a Predictor of Exacerbations in Patients with Chronic Obstructive Pulmonary Disease
Furukawa Y, Miyamoto A, Asai K, Tsutsumi M, Hirai K, Ueda T, Toyokura E, Nishimura M, Sato K, Yamada K, Watanabe T, Kawaguchi T
Respirology. 2025 May;30(5):408-416. doi: 10.1111/resp.70003. Epub 2025 Feb 26.PMID: 40009650
Efficacy of ramucirumab combined with erlotinib or osimertinib in untreated EGFR-mutated NSCLC patients with asymptomatic brain metastases: insights from molecular biomarkers in the RELAY-brain trial
Kaneda H, Daga H, Okada A, Nakatani Y, Tani Y, Oka T, Sawa K, Sakai K, Nishio K, Kawaguchi T
Invest New Drugs. 2025 Feb;43(1):147-156. doi: 10.1007/s10637-025-01505-y. Epub 2025 Jan 23.PMID: 39847172
Establishing a new human lung squamous cell carcinoma cell line, OMUL-1, expressing insulin-like growth factor 1 receptor and programmed cell death ligand 1
Nagamine H, Yashiro M, Mizutani M, Sugimoto A, Matsumoto Y, Tani Y, Kaneda H, Yamada K, Watanabe T, Asai K, Suzuki S, Kawaguchi T
Thorac Cancer. 2025 Jan;16(1):e15488. doi: 10.1111/1759-7714.15488. Epub 2024 Nov 17.PMID: 39552203
Application and Advancement of Bronchoscopic Biopsy Techniques for the Diagnosis of Pulmonary Nodules
Wang L, Miao Y, Kaneda H, Kawaguchi T, Sheng Y, Gu Y, Mizutani M, Watanabe T, Asai K, Zhang H, Tani Y, Nakai T
Respiratory Endoscopy.November 2024;2(3):122-127
Insulin-like growth factor 1 receptor expression correlates with programmed death ligand 1 expression and poor survival in non-small cell lung cancer.
Nagamine H, Yashiro M, Mizutani M, Sugimoto A, Matsumoto Y, Tani Y, Sawa K,Kaneda H, Yamada K, Watanabe T, Asai K, Suzuki S, Kawaguchi T
PLoS One. 2024 Oct 4;19(10):e0297397. doi: 10.1371/journal.pone.0297397. eCollection 2024.PMID: 39365756
Randomized controlled trial to examine the tolerability of bronchoscopy with and without pharyngeal laryngeal anesthesia (TACOYAKI study)
Ueda T, Tanaka H, Ueno K, Kobayashi M, Kadotani H, Uenishi R, Ishii M, Takeda N, Matsushita H, Kawaguchi T
Randomized Controlled Trial Respir Investig. 2024 Sep;62(5):867-871. doi: 10.1016/j.resinv.2024.07.007. Epub 2024 Jul 27.PMID: 39068896
Derived neutrophil-to-lymphocyte ratio has the potential to predict safety and outcomes of durvalumab after chemoradiation in non-small cell lung cancer
Sugimoto A, Kaneda H, Yoshimoto N, Nagata K, Fujii T, Michimoto K, Ueno S, Kamimori T, Ishii Y, Sakagami M, Inokuchi H, Shibuya K, Mizutani M, Nagamine H, Nakahama K, Matsumoto Y, Tani Y, Sawa K, Kawaguchi T
Sci Rep. 2024 Aug 23;14(1):19596. doi: 10.1038/s41598-024-70214-y.PMID: 39179598
Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes.
Yamada K, St Croix C, Stolz DB, Tyurina YY, Tyurin VA, Bradley LR, Kapralov AA, Deng Y, Zhou X, Wei Q, Liao B, Fukuda N, Sullivan M, Trudeau J, Ray A, Kagan VE, Zhao J, Wenzel SE
Nat Commun. 2024 Jul 10;15(1):5818. doi: 10.1038/s41467-024-50222-2.PMID: 38987265
Lack of Association Between Immunotherapy and Improvement of Survival for Non-small Cell Lung Cancer Patients With Hemodialysis: A Nationwide Retrospective Cohort Study
Sawa K, Ihara Y, Imai T, Sugimoto A, Nagamine H, Ogawa K, Nakahama K, Matsumoto Y, Tani Y, Kaneda H, Mitsuoka S, Kawaguchi T, Shintani A.
Clin Lung Cancer. 2024 Mar;25(2):144-150.e3. doi: 10.1016/j.cllc.2023.11.003. Epub 2023 Nov 7.PMID: 38042690
Comparison of the specimen quality of endobronchial ultrasound-guided intranodal forceps biopsy using standard-sized forceps versus mini forceps for lung cancer: A prospective study
Nakai T, Matsumoto Y, Ueda T, Kuwae Y, Tanaka S, Miyamoto A, Matsumoto Y, Sawa K, Sato K, Yamada K, Watanabe T, Asai K, Furuse H, Uchimura K, Imabayashi T, Uenishi R, Fukui M, Tanaka H, Ohsawa M, Kawaguchi T, Tsuchida T.
Respirology. 2024 May;29(5):396-404. doi: 10.1111/resp.14659. Epub 2024 Jan 21.PMID: 38246887
Clinical significance of KL-6 in immune-checkpoint inhibitor treatment for non-small cell lung cancer
Nakahama K, Izumi M, Yoshimoto N, Fukui M, Sugimoto A, Nagamine H, Ogawa K, Sawa K, Tani Y, Kaneda H, Mitsuoka S, Watanabe T, Asai K, Kawaguchi T.
Cancer Chemother Pharmacol. 2023 Nov;92(5):381-390. doi: 10.1007/s00280-023-04573-0. Epub 2023 Aug 22.PMID: 37606723
RBM17 Expression Is Associated With the Efficacy of ICI Monotherapy in NSCLC With Low PD-L1 Expression
Nagamine H, Yashiro M, Yoshimoto N, Izumi M, Sugimoto A, Nakahama K, Ogawa K, Matsumoto Y, Sawa K, Tani Y, Kaneda H, Mitsuoka S, Yamada K, Watanabe T, Aasai K, Fukumura K, Mayeda A, Kawaguchi T.
Anticancer Res. 2023 Oct;43(10):4663-4672. doi: 10.21873/anticanres.16662.PMID: 37772582
Diagnostic Utility and Safety of Non-Intubated Cryobiopsy Technique Using a Novel Ultrathin Cryoprobe in Addition to Conventional Biopsy Techniques for Peripheral Pulmonary Lesions
Nakai T, Watanabe T, Kaimi Y, Shiomi K, Ando K, Miyamoto A, Ogawa K, Matsumoto Y, Sawa K, Sato K, Asai K, Matsumoto Y, Mikami Y, Ohsawa M, Kawaguchi T.
Respiration. 2023;102(7):503-514. doi: 10.1159/000531010. Epub 2023 Jun 28.PMID: 37379810
Influence of Smoking History on the Effectiveness of Immune-checkpoint Inhibitor Therapy for Non-small Cell Lung Cancer: Analysis of Real-world Data
Nakahama K, Izumi M, Yoshimoto N, Fukui M, Sugimoto A, Nagamine H, Ogawa K, Sawa K, Tani Y, Kaneda H, Mitsuoka S, Watanabe T, Asai K, Kawaguchi T.
Anticancer Res. 2023 May;43(5):2185-2197. doi: 10.21873/anticanres.16381.PMID: 37097681
Distinct contributions of muscle mass and strength stratified by nutritional status to physical activity in patients with chronic obstructive pulmonary disease
Kawai T, Asai K, Miyamoto A, Yamada K, Furukawa Y, Toyokura E, Nishimura M, Sato K, Watanabe T, Kawaguchi T.
Respir Investig. 2023 Jul;61(4):389-397. doi: 10.1016/j.resinv.2023.03.001. Epub 2023 Apr 21.PMID: 37088061
A Large-Scale Prospective Concordance Study of Plasma- and Tissue-Based Next-Generation Targeted Sequencing for Advanced Non-Small Cell Lung Cancer (LC-SCRUM-Liquid)
Sugimoto A, Matsumoto S, Udagawa H, Itotani R, Usui Y, Umemura S, Nishino K, Nakachi I, Kuyama S, Daga H, Hara S, Miyamoto S, Kato T, Sakakibara-Konishi J, Tabata E, Nakagawa T, Kawaguchi T, Sakai T, Shibata Y, Izumi H, Nosaki K, Zenke Y, Yoh K, Goto K.
Clin Cancer Res. 2023 Apr 14;29(8):1506-1514. doi: 10.1158/1078-0432.CCR-22-1749.PMID: 36201167
Vimentin expression correlates with immune checkpoint inhibitor efficacy in non-small cell lung cancer
Nakahama K, Izumi M, Yoshimoto N, Fukui M, Sugimoto A, Nagamine H, Ogawa K, Sawa K, Tani Y, Kaneda H, Mitsuoka S, Watanabe T, Asai K, Kawaguchi T.
Cancer. 2023 Aug 1;129(15):2297-2307. doi: 10.1002/cncr.34782. Epub 2023 Apr 6.PMID: 37021822
Diagnostic efficacy of cryobiopsy for peripheral pulmonary lesions: A propensity score analysis
Furuse H, Matsumoto Y, Nakai T, Tanaka M, Nishimatsu K, Uchimura K, Imabayashi T, Tsuchida T, Ohe Y.
Lung Cancer. 2023 Apr:178:220-228. doi: 10.1016/j.lungcan.2023.02.022. Epub 2023 Mar 1.PMID: 36893563
Ethnic differences in lung cancer: "we can differ and still unite around common goals."
Kawaguchi T.
Respir Investig. 2023 May;61(3):355-356. doi: 10.1016/j.resinv.2023.02.002. Epub 2023 Mar 22.PMID: 36963275
The Impact of Estrogen Receptor Expression on Mutational Status in the Evolution of Non-Small Cell Lung Cancer
Tani Y, Kaneda H, Koh Y, Tamiya A, Isa S, Kubo A, Ogawa K, Matsumoto Y, Sawa K, Yoshimoto N, Mitsuoka S, Kawaguchi T.
Clin Lung Cancer. 2023 Mar;24(2):165-174. doi: 10.1016/j.cllc.2022.12.010. Epub 2022 Dec 31.PMID: 36646585
Rifampicin exerts anti-mucoviscous activity against hypervirulent Klebsiella pneumoniae via binding to the RNA polymerase β subunit
Tohda M, Oinuma KI, Sakiyama A, Tsubouchi T, Niki M, Namikawa H, Yamane K, Yamada K, Watanabe T, Asai K, Kakeya H, Kaneko Y, Kawaguchi T.
J Glob Antimicrob Resist. 2023 Mar:32:21-28. doi: 10.1016/j.jgar.2022.11.018. Epub 2022 Dec 23.PMID: 36572148
COVID-19 vaccination benefits in preventing severe disease in mild-to-moderate cases: An analysis in the first specialized hospital for COVID-19 in Japan
Kobayashi M, Miyamoto A, Watanabe T, Sawa K, Sato K, Yamada K, Yoshii N, Yamada K, Kawamoto K, Uji M, Shiraishi S, Asai K, Kakeya H, Kawaguchi T.
Respir Investig. 2023 Mar;61(2):230-239. doi: 10.1016/j.resinv.2022.12.011. Epub 2023 Feb 2.PMID: 36774816
A Culture Supernatant from an Actinomycete sp. Affects Biofilm Formation and Virulence Expression of Candida auris
Yamane K, Niki M, Tsubouchi T, Watanabe T, Asai K, Oinuma KI, Sakiyama A, Saren C, Matsumoto Y, Makimura K, Kaneko Y, Kawaguchi T.
Med Mycol J. 2023;64(1):7-17. doi: 10.3314/mmj.22-00026.PMID: 36858631
Association of combustible cigarettes and heated tobacco products use with SARS-CoV-2 infection and severe COVID-19 in Japan: a JASTIS 2022 cross-sectional study
Nishimura M, Asai K, Tabuchi T, Toyokura E, Kawai T, Miyamoto A, Watanabe T, Kawaguchi T.
Sci Rep. 2023 Feb 2;13(1):1120. doi: 10.1038/s41598-023-28006-3.PMID: 36732559
SP142 evaluation contributes to the prediction of immune checkpoint inhibitor efficacy in non-small cell lung cancer with high PD-L1 expression assessed by 22C3
Nakahama K, Osawa M, Izumi M, Yoshimoto N, Sugimoto A, Nagamine H, Ogawa K, Matsumoto Y, Sawa K, Tani Y, Kaneda H, Mitsuoka S, Watanabe T, Asai K, Kawaguchi T.
Transl Lung Cancer Res. 2022 Dec;11(12):2438-2451. doi: 10.21037/tlcr-22-496.PMID: 36636414
Vascular endothelial growth factor receptor 2 expression and immunotherapy efficacy in non-small cell lung cancer
Nakahama K, Kaneda H, Osawa M, Fukui M, Izumi M, Yoshimoto N, Sugimoto A, Nagamine H, Ogawa K, Matsumoto Y, Sawa K, Tani Y, Mitsuoka S, Watanabe T, Asai K, Kawaguchi T.
Cancer Sci. 2022 Sep;113(9):3148-3160. doi: 10.1111/cas.15464. Epub 2022 Jul 18.PMID: 35722982
Association of thyroid transcription factor-1 with the efficacy of immune-checkpoint inhibitors in patients with advanced lung adenocarcinoma
Nakahama K, Kaneda H, Osawa M, Izumi M, Yoshimoto N, Sugimoto A, Nagamine H, Ogawa K, Matsumoto Y, Sawa K, Tani Y, Mitsuoka S, Watanabe T, Asai K, Kawaguchi T.
Thorac Cancer. 2022 Aug;13(16):2309-2317. doi: 10.1111/1759-7714.14560. Epub 2022 Jul 8.PMID: 35808895
Prognostic impact of pretreatment T790M mutation on outcomes for patients with resected, EGFR-mutated, non-small cell lung cancer
Matsumoto Y, Kawaguchi T, Watanabe M, Isa SI, Ando M, Tamiya A, Kubo A, Kitagawa C, Yoshimoto N, Koh Y.
BMC Cancer. 2022 Jul 15;22(1):775. doi: 10.1186/s12885-022-09869-7.PMID: 35840951
Vascular endothelial growth factor receptor 2 expression and immunotherapy efficacy in non-small cell lung cancer
Nakahama K, Kaneda H, Osawa M, Fukui M, Izumi M, Yoshimoto N, Sugimoto A, Nagamine H, Ogawa K, Matsumoto Y, Sawa K, Tani Y, Mitsuoka S, Watanabe T, Asai K, Kawaguchi T
Cancer Sci. 2022 Sep;113(9):3148-3160. doi: 10.1111/cas.15464. Epub 2022 Jul 18.PMID: 35722982
Safety profile and risk factors for bleeding in transbronchial cryobiopsy using a two-scope technique for peripheral pulmonary lesions
Nakai T, Watanabe T, Kaimi Y, Ogawa K, Matsumoto Y, Sawa K, Okamoto A, Sato K, Asai K, Matsumoto Y, Ohsawa M, Kawaguchi T
BMC Pulm Med. 2022 Jan 10;22(1):20. doi: 10.1186/s12890-021-01817-8.PMID: 35000601