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以下の通り生物学専攻セミナーを開催します．

日時：10/10  15:00－16:30

場所：理学部G棟 サイエンスホール

演者：David Dolezel 博士（Laboratory of Molecular Chronobiology, Institute of Entomology, Biology Centre, Czech Academy of Science）

タイトル：Evolution of Circadian Clocks and Clock Genes in Animals

As we live in a periodic environment, nearly all organisms possess internal time-keeping devices, known as circadian clocks, which orchestrate an organism's physiology, metabolism, and activity within the Earth’s 24-hour cycle. These clocks are well studied at the molecular and genetic levels in model organisms such as the fruit fly Drosophila or the mouse. Although the majority of genes and underlying mechanisms are conserved among flies and mammals, there are several important differences. For example, various insect species contain different combinations of Drosophila and mammalian clock components. Furthermore, mammalian genomes have undergone several near-complete genome duplications, resulting in various levels of clock gene multiplication, further shaped by secondary gene losses.

     In this seminar, I will present our recent data addressing the evolution of circadian clock genes across animals ? from the earliest available single-cell organisms to humans ? and describe some lineages of animals with unusual clock setups or remarkable gene modifications. I will highlight some interesting twists in the origin of mammalian clock genes. Finally, I would like to illustrate how phylogenetic comparisons inspire exciting experimental research directions and share our recent reverse genetic data on unique clock components in insects.

※ 生物学専攻セミナーは、博士後期課程の「◯◯生物学ゼミナール」の授業の一部となっています（4月のカリキュラムオリエンテーションで説明済み）。生物学専攻セミナーを受講した博士後期課程の学生は、授業後に質問や感想を書いたファイル等を（セミナーごとの指示にしたがって）自身が履修登録している「◯◯生物学ゼミナール」の科目代表教員（機能解析生物学ゼミナール、藤田先生 (fujita@) ；生体機能生物学ゼミナール、宮田先生 (miyata@)；自然誌機能生物学ゼミナール、安房田先生 (sa-awata@)）に提出してください。

問い合わせ：後藤慎介